Structure of PDB 4b86 Chain L Binding Site BS01

Receptor Information
>4b86 Chain L (length=112) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MNPVNATALYISASRLVLNYDPKAFTEINRLLPYFRQSLSCCVCGHLLQD
PIAPTNSTCQHYVCKTCKGKKMMMKPSCSWCKDYEQFEENKQLSILVNCY
KKLCEYITQTTL
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain4b86 Chain L Residue 201 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB4b86 Msl1-Mediated Dimerization of the Dosage Compensation Complex is Essential for Male X-Chromosome Regulation in Drosophila.
Resolution3.5 Å
Binding residue
(original residue number in PDB)		C44 C47 C67
Binding residue
(residue number reindexed from 1)		C41 C44 C64
Annotation score4
Enzymatic activity
Enzyme Commision number 2.3.2.27: RING-type E3 ubiquitin transferase.
Gene Ontology
Molecular Function
GO:0061630 ubiquitin protein ligase activity
Cellular Component
GO:0072487 MSL complex

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Molecular Function
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Cellular Component
External links
PDB RCSB:4b86, PDBe:4b86, PDBj:4b86
PDBsum4b86
PubMed23084835
UniProtQ9HCI7|MSL2_HUMAN E3 ubiquitin-protein ligase MSL2 (Gene Name=MSL2)

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