Structure of PDB 2ykr Chain L Binding Site BS01

Receptor Information
>2ykr Chain L (length=123) Species: 668369 (Escherichia coli DH5[alpha]) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
ATVNQLVRKPRARKVAKSNVPALEACPQKRGVCTRVYTTTPKKPNSALRK
VCRVRLTNGFEVTSYIGGEGHNLQEHSVILIRGGRVKDLPGVRYHTVRGA
LDCSGVKDRKQARSKYGVKRPKA
Ligand information
>2ykr Chain A (length=1533) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
aauugaagaguuugaucauggcucagauugaacgcuggcggcaggccuaa
cacaugcaagucgaacgguaacaggaagaagcuugcuucuuugcugacga
guggcggacgggugaguaaugucugggaaacugccugauggagggggaua
acuacuggaaacgguagcuaauaccgcauaacgucgcaagaccaaagagg
gggaccuucgggccucuugccaucggaugugcccagaugggauuagcuag
uaggugggguaacggcucaccuaggcgacgaucccuagcuggucugagag
gaugaccagccacacuggaacugagacacgguccagacuccuacgggagg
cagcaguggggaauauugcacaaugggcgcaagccugaugcagccaugcc
gcguguaugaagaaggccuucggguuguaaaguacuuucagcggggagga
agggaguaaaguuaauaccuuugcucauugacguuacccgcagaagaagc
accggcuaacuccgugccagcagccgcgguaauacggagggugcaagcgu
uaaucggaauuacugggcguaaagcgcacgcaggcgguuuguuaagucag
augugaaauccccgggcucaaccugggaacugcaucugauacuggcaagc
uugagucucguagagggggguagaauuccagguguagcggugaaaugcgu
agagaucuggaggaauaccgguggcgaaggcggcccccuggacgaagacu
gacgcucaggugcgaaagcguggggagcaaacaggauuagauacccuggu
aguccacgccguaaacgaugucgacuuggagguugugcccuugaggcgug
gcuuccggagcuaacgcguuaagucgaccgccuggggaguacggccgcaa
gguuaaaacucaaaugaauugacgggggcccgcacaagcgguggagcaug
ugguuuaauucgaugcaacgcgaagaaccuuaccuggucuugacauccac
ggaaguuuucagagaugagaaugugccuucgggaaccgugagacaggugc
ugcauggcugucgucagcucguguugugaaauguuggguuaagucccgca
acgagcgcaacccuuauccuuuguugccagcgguccggccgggaacucaa
aggagacugccagugauaaacuggaggaagguggggaugacgucaaguca
ucauggcccuuacgaccagggcuacacacgugcuacaauggcgcauacaa
agagaagcgaccucgcgagagcaagcggaccucauaaagugcgucguagu
ccggauuggagucugcaacucgacuccaugaagucggaaucgcuaguaau
cguggaucagaaugccacggugaauacguucccgggccuuguacacaccg
cccgucacaccaugggaguggguugcaaaagaaguagguagcuuaaccuu
cgggagggcgcuuaccacuuugugauucaugacuggggugaagucguaac
aagguaaccguaggggaaccugcgguuggauca
.......<<<<..[.(((..>>>>......<<<<<..<<<<<........
<<..<<...........<....<.....................>..>..
...........<..........<<<<........<<<<<...<.<.....
.<<............>>.......>.>....................<<.
.....<....>....>>....>>>>>......>>>>..<<<.........
.<<<<.............>>>>..........>>>..<<<<..<<....>
>.....>>>>..>..<<<<............>>>>...............
...>>.>>.........<<.....<<<<....>>>>...>>......>>>
>>.............<<<....>>>...............<<<<<.....
.<.........................>........>>>>>.......<<
<<<(((...<<<<.........)))..........>>>>>>>>>..>>>>
>.................((......<<<...<......<..<.<<...<
<<<........<<<<.......>>>>......>>>>.....>>>..>...
...<<<<<<.....<<<<<......<.<.<.<..................
.....>.>.>..>..........<<....>>...>>>>>....>>.>>>>
.....>...>>>.....<<<<<.....<....<.............>...
.>..>>>>>..........<<<<<<..<<<<<<<<<<.........>>>>
>>>>>>...<<..))>>.....>>>>>>.....<<........<......
..>......>>...))).]..<...<<<<<<<.....<<<....<<<<<<
<...............................<<<<<<........<<<<
<.......<<<....>>>.......<<....>>...>>>>.>..<<<.<<
<..<.<<<........<<<<<<<<......>>....<........>....
>>>>>>............<<<..........<<.....>>.........>
>>.........<<<.....>>>........................>...
>>.>>>>>>>....>>>>>>.......>>>>>>>......<<.<......
.<<<..<<...<<<....>>>...>>....>>>.......>.>>......
......<<<<<.<........>.>>>>>............>>>.....<<
<..<...........>..>>>...........>>>>>>>..>........
.......<<<<.<.......<<<<<........<<.......<<..<<..
..>>.>>......>>.......>>>>>.......>.>>>>..........
.....<<<<<<<<<....>>>>>>>>>......
Receptor-Ligand Complex Structure
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PDB2ykr Structural Basis for the Function of a Small Gtpase Rsga on the 30S Ribosomal Subunit Maturation Revealed by Cryoelectron Microscopy.
Resolution9.8 Å
Binding residue
(original residue number in PDB)		T2 N4 Q5 R8 K9 R11 A12 R13 K14 V15 A16 K17 S18 N19 V20 P21 L23 E24 A25 C26 P27 Q28 K29 R30 K43 P44 N45 S46 A47 L48 R49 K50 T57 N58 Y65 G68 E69 R82 R85 K87 D88 P90 G91 R93 Y94 A100 L101 D108 R109 K110 Q111 A112 R113 S114 K115 Y116 K119 R120 P121 K122 A123
Binding residue
(residue number reindexed from 1)		T2 N4 Q5 R8 K9 R11 A12 R13 K14 V15 A16 K17 S18 N19 V20 P21 L23 E24 A25 C26 P27 Q28 K29 R30 K43 P44 N45 S46 A47 L48 R49 K50 T57 N58 Y65 G68 E69 R82 R85 K87 D88 P90 G91 R93 Y94 A100 L101 D108 R109 K110 Q111 A112 R113 S114 K115 Y116 K119 R120 P121 K122 A123
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0000049 tRNA binding
GO:0003735 structural constituent of ribosome
GO:0005515 protein binding
GO:0019843 rRNA binding
GO:0034336 misfolded RNA binding
Biological Process
GO:0000372 Group I intron splicing
GO:0002181 cytoplasmic translation
GO:0006412 translation
GO:0033120 positive regulation of RNA splicing
GO:0034337 RNA folding
GO:0046677 response to antibiotic
GO:1990145 maintenance of translational fidelity
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005840 ribosome
GO:0015935 small ribosomal subunit
GO:0022627 cytosolic small ribosomal subunit
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:2ykr, PDBe:2ykr, PDBj:2ykr
PDBsum2ykr
PubMed21788480
UniProtP0A7S3|RS12_ECOLI Small ribosomal subunit protein uS12 (Gene Name=rpsL)

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