Structure of PDB 2c0b Chain L Binding Site BS01

Receptor Information
>2c0b Chain L (length=488) Species: 562 (Escherichia coli) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
AHIEGRHMKRMLINATQQEELRVALVDGQRLYDLDIESPEQKKANIYKGK
ITRIEAAFVDYGAERHGFLPLKEIAREYFPRPNIKDVLREGQEVIVQIDK
EERGNKGAALTTFISLAGSYLVLMPNNPRAGGISRRIELKEALASLELPL
IVRTAGVGKSAEALQWDLSFRLKHWEAIKKAAESRPAPFLIHQESNVIVR
AFRDYLRQDIGEILIDNPKVLELARQHIAALGRPDFSSKIKLYTGEIPLF
SHYQIESQIESAFQREVRLPSGGSIVIDSTEALTAIDINSARDIEETAFN
TNLEAADEIARQLRLRDLGGLIVIDFIDMTPVRHQRAVENRLREAVRQDR
ARIQISHISRFGLLEMSRQRLSPSLGESSHHVCPRCSGTGTVRDNESLSL
SILRLIEEEALKENTQEVHAIVPVPIASYLLNEKRSAVNAIETRQDGVRC
VIVPNDQMETPHYHVLRVRKGEETPTLSYMLPKLHEEA
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB2c0b Structure of E. Coli Rnase E Catalytic Domain and Implications for RNA Processing and Turnover
Resolution3.18 Å
Binding residue
(original residue number in PDB)		F67 K106 K112 G113 G137 G138 I139 S140 I167 R169 T170 L342 R373 Q390 R391
Binding residue
(residue number reindexed from 1)		F68 K100 K106 G107 G131 G132 I133 S134 I151 R153 T154 L321 R352 Q369 R370
Enzymatic activity
Enzyme Commision number 3.1.26.12: ribonuclease E.
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0003723 RNA binding
GO:0004540 RNA nuclease activity
GO:0008995 ribonuclease E activity
Biological Process
GO:0006396 RNA processing

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Molecular Function
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Biological Process
External links
PDB RCSB:2c0b, PDBe:2c0b, PDBj:2c0b
PDBsum2c0b
PubMed16237448
UniProtP21513|RNE_ECOLI Ribonuclease E (Gene Name=rne)

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