Structure of PDB 2bx2 Chain L Binding Site BS01

Receptor Information
>2bx2 Chain L (length=500) Species: 562 (Escherichia coli) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
AHIEGRHMKRMLINATQQEELRVALVDGQRLYDLDIESPGHEQKKANIYK
GKITRIEPSLEAAFVDYGAERHGFLPLKEIAREYFPRPNIKDVLREGQEV
IVQIDKEERGNKGAALTTFISLAGSYLVLMPNNPRAGGISRRIELKEALA
SLELPEGMGLIVRTAGVGKSAEALQWDLSFRLKHWEAIKKAAESRPAPFL
IHQESNVIVRAFRDYLRQDIGEILIDNPKVLELARQHIAALGRPDFSSKI
KLYTGEIPLFSHYQIESQIESAFQREVRLPSGGSIVIDSTEALTAIDINS
ARGDIEETAFNTNLEAADEIARQLRLRDLGGLIVIDFIDMTPVRHQRAVE
NRLREAVRQDRARIQISHISRFGLLEMSRQRLSPSLGESSHHVCPRCSGT
GTVRDNESLSLSILRLIEEEALKENTQEVHAIVPVPIASYLLNEKRSAVN
AIETRQDGVRCVIVPNDQMETPHYHVLRVRKGEETPTLSYMLPKLHEEAM
Ligand information
Receptor-Ligand Complex Structure
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PDB2bx2 Structure of E. Coli Rnase E Catalytic Domain and Implications for RNA Processing and Turnover
Resolution2.85 Å
Binding residue
(original residue number in PDB)		V128 A136 G137 G138 I139 S140 R141 I167 R169 T170 R373
Binding residue
(residue number reindexed from 1)		V128 A136 G137 G138 I139 S140 R141 I161 R163 T164 R363
Enzymatic activity
Enzyme Commision number 3.1.26.12: ribonuclease E.
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0003723 RNA binding
GO:0004540 RNA nuclease activity
GO:0008995 ribonuclease E activity
Biological Process
GO:0006396 RNA processing

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Molecular Function
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Biological Process
External links
PDB RCSB:2bx2, PDBe:2bx2, PDBj:2bx2
PDBsum2bx2
PubMed16237448
UniProtP21513|RNE_ECOLI Ribonuclease E (Gene Name=rne)

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