Structure of PDB 1qdu Chain L Binding Site BS01
Receptor Information
>1qdu Chain L (length=88) Species:
9606
(Homo sapiens) [
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TRYIPDEADFLLGMATVNNCVSYRNPAEGTWYIQSLCQSLRERCPRGDDI
LTILTEVNYEVSNKDDKKNMGKQMPQPTFTLRKKLVFP
Ligand information
>1qdu Chain Y (length=4) [
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tEVD
Receptor-Ligand Complex Structure
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PDB
1qdu
The three-dimensional structure of caspase-8: an initiator enzyme in apoptosis.
Resolution
2.8 Å
Binding residue
(original residue number in PDB)
S339 Y340 R341 N342
Binding residue
(residue number reindexed from 1)
S22 Y23 R24 N25
Enzymatic activity
Enzyme Commision number
3.4.22.61
: caspase-8.
Gene Ontology
Molecular Function
GO:0004197
cysteine-type endopeptidase activity
GO:0008234
cysteine-type peptidase activity
Biological Process
GO:0006508
proteolysis
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Molecular Function
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Biological Process
External links
PDB
RCSB:1qdu
,
PDBe:1qdu
,
PDBj:1qdu
PDBsum
1qdu
PubMed
10508784
UniProt
Q14790
|CASP8_HUMAN Caspase-8 (Gene Name=CASP8)
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