Structure of PDB 6woo Chain KK Binding Site BS01

Receptor Information
>6woo Chain KK (length=96) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MLMPKEDRNKIHQYLFQEGVVVAKKDFNQAKHEEIDTKNLYVIKALQSLT
SKGYVKTQFSWQYYYYTLTEEGVEYLREYLNLPEHIVPATYIQERN
Ligand information
>6woo Chain 2 (length=1780) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
aucugguugauccugccaguagucauaugcuugucucaaagauuaagcca
ugcaugucuaaguauaagcaauuuauacagugaaacugcgaauggcucau
uaaaucaguuaucguuuauuugauaguuccuuuacuacaugguauaacug
ugguaauucuagagcuaauacaugcuuaaaaucucgacccuuuggaagag
auguauuuauuagauaaaaaaucaaugucuucggacucuuugaugauuca
uaauaacuuuucgaaucgcauggccuugugcuggcgaugguucauucaaa
uuucugcccuaucaacuuucgaugguaggauaguggccuaccaugguuuc
aacggguaacggggaauaaggguucgauuccggagagggagccugagaaa
cggcuaccacauccaaggaaggcagcaggcgcgcaaauuacccaauccua
auucagggagguagugacaauaaauaacgauacagggcccauucgggucu
uguaauuggaaugaguacaauguaaauaccuuaacgaggaacaauuggag
ggcaagucuggugccagcagccgcgguaauuccagcuccaauagcguaua
uuaaaguuguugcaguuaaaaagcucguaguugaacuuugggcccgguug
gccggucgauuuuccaacggggccuuuccuucuggcuaaccuugaguccu
uguggcucuuggcgaaccaggacuuuuacuuugaaaaaauuagaguguuc
aaagcaggcguauugcucgaauauauuagcauggaauaauagaauaggac
guuugguucuauuuuguugguuucuaggaccaucguaaugauuaauaggg
acggucgggggcaucaguauucaauugucagaggugaaauucuuggauuu
auugaagacuaacuacugcgaaagcauuugccaaggacguuuucauuaau
caagaacgaaaguuaggggaucgaagaugaucagauaccgucguagucuu
aaccauaaacuaugccgacuagggaucgggugguguuuuuuuaaugaccc
acucggcaccuuacgagaaaucaaagucuuuggguucuggggggaguaug
gucgcaaggcugaaacuuaaaggaauugacggaagggcaccaccaggagu
ggagccugcggcuuaauuugacucaacacggggaaacucaccagguccag
acacaauaaggauugacagauugagagcucuuucuugauuuugugggugg
uggugcauggccguucuuaguugguggagugauuugucugcuuaauugcg
auaacgaacgagaccuuaaccuacuaaauaguggugcuagcauuugcugg
uuauccacuucuuagagggacuaucgguuucaagccgauggaaguuugag
gcaauaacaggucugugaugcccuuagacguucugggccgcacgcgcgcu
acacugacggagccagcgagucuaaccuuggccgagaggucuugguaauc
uugugaaacuccgucgugcuggggauagagcauuguaauuauugcucuuc
aacgaggaauuccuaguaagcgcaagucaucagcuugcguugauuacguc
ccugcccuuuguacacaccgcccgucgcuaguaccgauugaauggcuuag
ugaggccucaggaucugcuuagagaagggggcaacuccaucucagagcgg
agaauuuggacaaacuuggucauuuagaggaacuaaaagucguaacaagg
uuuccguaggugaaccugcggaaggaucau
..<<<<<.{.[[[[>>>>><<<<.<<<<<<...<.<...<......<<<.
<<<..<<....<<....<<..........>>...>>.>>......<<...
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<<<.....>>>.>>......>>........<<<<<............>>>
>><...<<<<<<......((((((..<<<....>>>....<<......>>
>>>>>>.....>...<<<<..<<<.....>>>.>>>>....>>>...>>>
>..>>>.<<<....<<<....<<<<<<<<.......>>>>>>>>>>>...
...>>>...<<<.<<<<....>>>>....>>>.>>.<<.<<<........
..>>>.>>.<.<<....>>.>...>>>>>>.........<<<....<<<.
....>>>..>>>..>....>.>.....<<<<<<<<<..<......>..>>
>>>>.>>>......<<..<...........>..>>.........<<<<<(
(......<<<<.....<<..))>>.......>>>>.>>>>>..>>>>>>>
>>>.........<<<[[.....<.<<...<<<........<<<<<.<<<<
.....<..>.....>>>>.>>>>>......<<<<.....<<....<<...
....>>....>>.....>>>>....<<<<<.<<.......<<...<....
...>..<<<.....>>>....>>......>>.>>..>>>.........<<
<..<<<<<<<<......)))))).>>>>>>>>.>>>...........<<<
<<<.<<...<<<<..<<..<<<<<<.<...<<<......>>>......>.
>>>>>>..>>.......<<....>>...>>>>...>>>>>.>>>...>>>
...>>.>....<<<<<.....<...<<<<.<.....>.>>>>...>..>>
>>>..........<<<.<<..<<..<<<<<<<<.<<<........>>>>>
>>>>>>..>>....<<..]]>>...>>.....>>>.>>>.<<<......<
<<<....>>>>....>>>..]]]].}<<<<<.<<<<<<<..<<.<<<<<<
..<<<.<<<<<<......<<........>>..........<<<<<.....
.<<<<<........<<.<<<........>>>.>>......>>>>>...<<
.<<<..<<<<<<<<<....<<<.<<<<<....>>>...<<<......>>>
...>>.>>>....<<<<<.<<..<<<<..<<<<<.<<<<<<....>>>>>
>...>>>>>..>>>>.>>....<<<<<<.....>>>>>>.......>>>>
>....>>>.>>>...>.>>>>>>>.......>>>>>...>>.>>>>.>>>
.....<<<<<<<......<<.....<<..<<<<....>>>>..>>....>
>.......>>>>>>>...........<<<<<<..........>>>>>>..
........>>>>>>....<<<<<<<<.......>>>>>>>>......>>.
..>>>>>>>>>>.>>....<..<<.<..<<<<.<<....<<<<<<<<.<<
<..<.<<..<...<<<<<............................>>>>
>...>..>>.>..>>>.>>>>>>>>...>>.>>>>...>.>>...>....
.<<<<<<<<<<..>>>>>>>>>>.......
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6woo An active role of the eukaryotic large ribosomal subunit in translation initiation fidelity.
Resolution2.9 Å
Binding residue
(original residue number in PDB)		M1 L2 M3 K25 F27 K44 Q47 S48 S51 K52 F59 Y64
Binding residue
(residue number reindexed from 1)		M1 L2 M3 K25 F27 K44 Q47 S48 S51 K52 F59 Y64
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003735 structural constituent of ribosome
GO:0005515 protein binding
Biological Process
GO:0000054 ribosomal subunit export from nucleus
GO:0002181 cytoplasmic translation
GO:0034198 cellular response to amino acid starvation
GO:0045860 positive regulation of protein kinase activity
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005840 ribosome
GO:0022627 cytosolic small ribosomal subunit
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:6woo, PDBe:6woo, PDBj:6woo
PDBsum6woo
PubMed
UniProtQ08745|RS10A_YEAST Small ribosomal subunit protein eS10A (Gene Name=RPS10A)

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