Structure of PDB 9gaw Chain K Binding Site BS01

Receptor Information
>9gaw Chain K (length=518) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MNLERLRKRVRQYLDQQQYQSALFWADKVASLSREEPQDIYWLAQCLYLT
AQYHRAAHALRSRKLDKLYEACRYLAARCHYAAKEHQQALDVLDMSIKSS
ICLLRGKIYDALDNRTLATYSYKEALKLDVYCFEAFDLLTSHHMLTAQEE
KELLESLPLSKLCNEEQELLRFLFENKLKKYNKPSETVIPESVDGLQENL
DVVVSLAERHYYNCDFKMCYKLTSVVMEKDPFHASCLPVHIGTLVELNKA
NELFYLSHKLVDLYPSNPVSWFAVGCYYLMVGHKNEHARRYLSKATTLEK
TYGPAWIAYGHSFAVESEHDQAMAAYFTAAQLMKGCHLPMLYIGLEYGLT
NNSKLAERFFSQALSIAPEDPFVMHEVGVVAFQNGEWKTAEKWFLDALEK
IKAIGNEVTVDKWEPLLNNLGHVCRKLKKYAEALDYHRQALVLIPQNAST
YSAIGYIHSLMGNFENAVDYFHTALGLRRDDTFSVTMLGHCIEMYIGYDF
DVHTMKTLKNIISPPWDF
Ligand information
>9gaw Chain W (length=26) Species: 9606 (Homo sapiens) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
MLRRKPTRLELKLDDIEEFENIRKDL
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB9gaw High-resolution structure of the Anaphase-promoting complex (APC/C) bound to co-activator Cdh1
Resolution2.9 Å
Binding residue
(original residue number in PDB)		Y242 Y243 F247 V270 V276 E277 H342 Y373 L376 H406 F413 K443 W444 E445 N449 N450 H453 R456 K457 N478 S480 A484 Y487 S490 L491 F514 H521 E524 M525
Binding residue
(residue number reindexed from 1)		Y211 Y212 F216 V239 V245 E246 H311 Y342 L345 H375 F382 K412 W413 E414 N418 N419 H422 R425 K426 N447 S449 A453 Y456 S459 L460 F483 H490 E493 M494
External links
PDB RCSB:9gaw, PDBe:9gaw, PDBj:9gaw
PDBsum9gaw
PubMed
UniProtQ13042|CDC16_HUMAN Cell division cycle protein 16 homolog (Gene Name=CDC16)

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