Structure of PDB 8v83 Chain K Binding Site BS01

Receptor Information
>8v83 Chain K (length=268) Species: 1247190 (Saccharomyces cerevisiae BY4741) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
AIPRERVIKAVNELIKFTSKPDDEEELKKDLQLIVVNNKSFTGTSKSFKL
KLLNVKHSFYKPWKEASATAVKDFKVLLILKDSDIKKVSEDDLFDQLDSE
GIKVDEIICGKDLKTVYKAYEARNAFISQFSLILADDSIVTSLPKLMGGK
AYNKVETTPISIRTHANKEFSLTTLTNNIKKVYMNQLPVKLPRGTTLNVH
LGNLEWLRPEEFVDNVELISEQLIKAYQIRSIFIKTNRSPVLPLYYNQDV
LDELESTFNKGLMEIANP
Ligand information
>8v83 Chain 6 (length=58) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
ccuucucaaacauguuugguagugagugauacucgaguuaacuugaaauu
gccuuaaa
......<<<<<..>>>>>.....<<<<.<.<<<..>>>>.>>>>......
........
Receptor-Ligand Complex Structure
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PDB8v83 The DEAD-box ATPase Dbp10/DDX54 initiates peptidyl transferase center formation during 60S ribosome biogenesis.
Resolution2.53 Å
Binding residue
(original residue number in PDB)		V83 F95 K96 K128 D129 K161 K165 A166 Y167 E168 D184 S185 V187 T188 S189 P191 K192 L193 G195 G196 K197 S208 N214 K215 T220 T221 N224 K228 P239 R240 T242 T243 N245 H247 R277 K282 N284 R285
Binding residue
(residue number reindexed from 1)		V36 F48 K49 K81 D82 K114 K118 A119 Y120 E121 D137 S138 V140 T141 S142 P144 K145 L146 G148 G149 K150 S161 N167 K168 T173 T174 N177 K181 P192 R193 T195 T196 N198 H200 R230 K235 N237 R238
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0005515 protein binding
GO:0019843 rRNA binding
GO:0030674 protein-macromolecule adaptor activity
GO:0042802 identical protein binding
GO:0070180 large ribosomal subunit rRNA binding
GO:0070628 proteasome binding
Biological Process
GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0000466 maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0030163 protein catabolic process
GO:0042254 ribosome biogenesis
Cellular Component
GO:0000502 proteasome complex
GO:0005634 nucleus
GO:0005730 nucleolus
GO:0030687 preribosome, large subunit precursor
GO:1990904 ribonucleoprotein complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8v83, PDBe:8v83, PDBj:8v83
PDBsum8v83
PubMed38632236
UniProtP38779|CIC1_YEAST Proteasome-interacting protein CIC1 (Gene Name=CIC1)

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