Structure of PDB 8utn Chain K Binding Site BS01

Receptor Information
>8utn Chain K (length=386) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
ASVKVAVRVRPFNSREMSRDSKCIIQMSGSTTTIVNPKQPKETPKSFSFD
YSYWSHTSPEDINYASQKQVYRDIGEEMLQHAFEGYNVCIFAYGQTGAGK
SYTMMGKQEKDQQGIIPQLCEDLFSRINDTTNDNMSYSVEVSYMEIYCER
VRDLLNPKNKGNLRVREHPLLGPYVEDLSKLAVTSYNDIQDLMDSGNKAR
TVAATNMNETSSRSHAVFNIIFTQKRHDAETNITTEKVSKISLVDLAGSE
RADSTGAKGTRLKEGANINKSLTTLGKVISALAEMDSGPNKNKKKKKTDF
IPYRDSVLTWLLRENLGGNSRTAMVAALSPADINYDETLSTLRYADRAKQ
IRCNAVINEDPNNKLIRELKDEVTRLRDLLYAQGLG
Ligand information
Ligand IDMG
InChIInChI=1S/Mg/q+2
InChIKeyJLVVSXFLKOJNIY-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mg+2]
CACTVS 3.341[Mg++]
FormulaMg
NameMAGNESIUM ION
ChEMBL
DrugBankDB01378
ZINC
PDB chain8utn Chain K Residue 501 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8utn Cryo-EM of human KIF1A reveals its mechanism of motility and the effect of its pathogenic variant P305L
Resolution3.1 Å
Binding residue
(original residue number in PDB)		S104 S215
Binding residue
(residue number reindexed from 1)		S101 S212
Annotation score4
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:8utn, PDBe:8utn, PDBj:8utn
PDBsum8utn
PubMed38956021
UniProtQ12756|KIF1A_HUMAN Kinesin-like protein KIF1A (Gene Name=KIF1A)

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