Structure of PDB 8uhe Chain K Binding Site BS01

Receptor Information
>8uhe Chain K (length=593) Species: 91464 (Synechococcus sp. PCC 7335) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
DRTNGGSPVVHPQQYHTVPTAVINGAHQRDRYPNHSEMQTLSTFLRTGLQ
RLEIAQTLAQHANEIVAAGFQAINIADYGAVRMKRSMRDLGWFLRYITYA
VVAGDTSIITVNTRGLRGIIPEDVTVATTVALQEMQWKSLSFFPVDSAAA
ALVRRYFDVLIADYQVEKPSDRYRTGVSKHDQGLSFPESYEDSGCAIPRW
VMKPTLPDSEKDAVIRAAYRQVFERDISGLGTAELTQPISQLKGEDGSME
LFIRQLGKSRLYRQLFYEPYMISRSIELACRHFLGRGLSCMEEFQRYFEL
VADQGFSALVDALVSSQEYADYFGAETVPYIRGLGIEAQACRNWGPQLDL
FKYSAPARKVPQFVTAFASYRQPLPNQHPYGMGNDPLETQFGAIFPHETT
NPAAQPVHFSEDSRRILVGHAHRKSHAEISQQIFSLQHSVESVILAAYRQ
VFGCEVLGSQRHQAAETQLKGGLITVREFVRQLAKSRSFRQAYWENLYMT
KAAEIIHRRLLGRPTYGRRETSKYYDICGRQGFYALVDALIDSDDYRTAF
GENTVPYERYVTPRGLALRSPKGPVAISKLRDNPHTVGEYMMR
Ligand information
Ligand IDM1V
InChIInChI=1S/C33H38N4O6/c1-7-20-19(6)32(42)37-27(20)14-25-18(5)23(10-12-31(40)41)29(35-25)15-28-22(9-11-30(38)39)17(4)24(34-28)13-26-16(3)21(8-2)33(43)36-26/h13-15,35H,7-12H2,1-6H3,(H,36,43)(H,37,42)(H,38,39)(H,40,41)/b26-13-,27-14-,28-15-
InChIKeyCXQHEXWJGZEPFP-BBROENKCSA-N
SMILES
SoftwareSMILES
OpenEye OEToolkits 1.7.6CCC1=C(/C(=C/C2=N/C(=C\c3c(c(c([nH]3)/C=C\4/C(=C(C(=O)N4)C)CC)C)CCC(=O)O)/C(=C2C)CCC(=O)O)/NC1=O)C
CACTVS 3.385CCC1=C(C)\C(NC1=O)=C\C2=NC(=C\c3[nH]c(\C=C4/NC(=O)C(=C4CC)C)c(C)c3CCC(O)=O)/C(=C2C)CCC(O)=O
OpenEye OEToolkits 1.7.6CCC1=C(C(=CC2=NC(=Cc3c(c(c([nH]3)C=C4C(=C(C(=O)N4)C)CC)C)CCC(=O)O)C(=C2C)CCC(=O)O)NC1=O)C
CACTVS 3.385CCC1=C(C)C(NC1=O)=CC2=NC(=Cc3[nH]c(C=C4NC(=O)C(=C4CC)C)c(C)c3CCC(O)=O)C(=C2C)CCC(O)=O
FormulaC33 H38 N4 O6
Namemesobiliverdin IX(alpha)
ChEMBL
DrugBank
ZINCZINC000086036419
PDB chain8uhe Chain K Residue 801 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8uhe Structure of the antenna complex expressed during far-red light photoacclimation in Synechococcus sp. PCC 7335.
Resolution2.78 Å
Binding residue
(original residue number in PDB)		R164 S165 R167 D168 W171 F172 N191 L195 I198 I199 P200 V203 T207
Binding residue
(residue number reindexed from 1)		R85 S86 R88 D89 W92 F93 N112 L116 I119 I120 P121 V124 T128
Annotation score1
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0015979 photosynthesis
Cellular Component
GO:0009579 thylakoid
GO:0016020 membrane
GO:0030089 phycobilisome
GO:0031676 plasma membrane-derived thylakoid membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8uhe, PDBe:8uhe, PDBj:8uhe
PDBsum8uhe
PubMed38141759
UniProtB4WKI6

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