Structure of PDB 8tj5 Chain K Binding Site BS01

Receptor Information
>8tj5 Chain K (length=217) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
QIQEQVLKCKESWDPNTTKTKLRAFVYNKVNETEAILYTKPGHVLQEEWD
QAMEKKPSPQTIPIQIYGFEGLNQRNQVQTENVAQARIILNHILEKSTQL
QQKHELDTASRILKAQSRNVEIEKRILKLGTQLATLKEEKMWSQFQTLLQ
RSEDPAGLGKTNELWARLAILKERAKNISSQINKIVEILTNQQRGITYLN
EVLEKDAAIVKKYKNKT
Ligand information
>8tj5 Chain 4 (length=16) Species: 4932 (Saccharomyces cerevisiae) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
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Receptor-Ligand Complex Structure
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PDB8tj5 Implications of a multiscale structure of the yeast nuclear pore complex.
Resolution6.6 Å
Binding residue
(original residue number in PDB)
N314 K315 V316 H378
Binding residue
(residue number reindexed from 1)
N28 K29 V30 H92
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005515 protein binding
GO:0017056 structural constituent of nuclear pore
GO:0042802 identical protein binding
Biological Process
GO:0006606 protein import into nucleus
GO:0006607 NLS-bearing protein import into nucleus
GO:0006913 nucleocytoplasmic transport
GO:0006999 nuclear pore organization
GO:0015031 protein transport
GO:0036228 protein localization to nuclear inner membrane
GO:0051028 mRNA transport
Cellular Component
GO:0005634 nucleus
GO:0005635 nuclear envelope
GO:0005643 nuclear pore
GO:0016020 membrane
GO:0031965 nuclear membrane
GO:0044613 nuclear pore central transport channel

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Biological Process

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Cellular Component
External links
PDB RCSB:8tj5, PDBe:8tj5, PDBj:8tj5
PDBsum8tj5
PubMed37738963
UniProtP48837|NUP57_YEAST Nucleoporin NUP57 (Gene Name=NUP57)

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