Structure of PDB 8t3w Chain K Binding Site BS01

Receptor Information
>8t3w Chain K (length=69) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
DEALVEELANFRTLVYCSLCSKNWKNMAIKTCGHVFCENCCKERLAARMR
KCPTCNKAFSSNDLLTVHL
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain8t3w Chain K Residue 801 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB8t3w Cryo-EM structure of Bre1-nucleosome complex in state 2
Resolution3.25 Å
Binding residue
(original residue number in PDB)		C663 H665 C683 C686
Binding residue
(residue number reindexed from 1)		C32 H34 C52 C55
Annotation score4
Enzymatic activity
Enzyme Commision number 2.3.2.27: RING-type E3 ubiquitin transferase.
Gene Ontology
Molecular Function
GO:0004842 ubiquitin-protein transferase activity

View graph for
Molecular Function
External links
PDB RCSB:8t3w, PDBe:8t3w, PDBj:8t3w
PDBsum8t3w
PubMed37872231
UniProtQ07457|BRE1_YEAST E3 ubiquitin-protein ligase BRE1 (Gene Name=BRE1)

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