Structure of PDB 8s4g Chain K Binding Site BS01

Receptor Information
>8s4g Chain K (length=531) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MNLERLRKRVRQYLDQQQYQSALFWADKVASLSREEPQDIYWLAQCLYLT
AQYHRAAHALRSRKLDKLYEACRYLAARCHYAAKEHQQALDVLDMEEPDW
EMSQSSIKSSICLLRGKIYDALDNRTLATYSYKEALKLDVYCFEAFDLLT
SHHMLTAQEEKELLESLPLSKLCNEEQELLRFLFENKLKKYNKPSETVIP
ESVDGLQENLDVVVSLAERHYYNCDFKMCYKLTSVVMEKDPFHASCLPVH
IGTLVELNKANELFYLSHKLVDLYPSNPVSWFAVGCYYLMVGHKNEHARR
YLSKATTLEKTYGPAWIAYGHSFAVESEHDQAMAAYFTAAQLMKGCHLPM
LYIGLEYGLTNNSKLAERFFSQALSIAPEDPFVMHEVGVVAFQNGEWKTA
EKWFLDALEKIKAIGNEVTVDKWEPLLNNLGHVCRKLKKYAEALDYHRQA
LVLIPQNASTYSAIGYIHSLMGNFENAVDYFHTALGLRRDDTFSVTMLGH
CIEMYIGCYDFDVHTMKTLKNIISPPWDFRE
Ligand information
Receptor-Ligand Complex Structure
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PDB8s4g New structural features of the APC/C revealed by high resolution cryo-EM structures of apo-APC/C and the APC/C-CDH1-EMI1 complex
Resolution
Binding residue
(original residue number in PDB)
Y242 Y243 F247 V270 V276 E277 A339 H342 Y373 L376 H406 F413 K443 W444 E445 P446 N449 N450 H453 R456 K457 N478 A484 Y487 S490 L491 F514 M518 H521 E524 M525
Binding residue
(residue number reindexed from 1)
Y221 Y222 F226 V249 V255 E256 A318 H321 Y352 L355 H385 F392 K422 W423 E424 P425 N428 N429 H432 R435 K436 N457 A463 Y466 S469 L470 F493 M497 H500 E503 M504
Enzymatic activity
Enzyme Commision number ?
External links