Structure of PDB 8phj Chain K Binding Site BS01

Receptor Information
>8phj Chain K (length=117) Species: 562 (Escherichia coli) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
RKQVSDGVAHIHASFNNTIVTITDRQGNALGWATAGGSGFRGSRKSTPFA
AQVAAERCADAVKEYGIKNLEVMVKGPGPGRESTIRALNAAGFRITNITD
VTPIPHDGCRPPKKRRV
Ligand information
>8phj Chain A (length=1503) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
aauugaagaguuugaucauggcucagauugaacgcuggcggcaggccuaa
cacaugcaagucgaacgguaacaggaaguuugcugacgaguggcggacgg
gugaguaaugucugggaaacugccugauggagggggauaacuacuggaaa
cgguagcuaauaccgcauaacgucgcaagaccaaagagggggccucuugc
caucggaugugcccagaugggauuagcuaguaggugggguaacggcucac
cuaggcgacgaucccuagcuggucugagaggaugaccagccacacuggaa
cugagacacgguccagacuccuacgggaggcagcaguggggaauauugca
caaugggcgcaagccugaugcagccaugccgcguguaugaagaaggccuu
cggguuguaaaguacuuucagcggggaggaagggaguaaaguuaauaccu
uugcucauugacguuacccgcagaagaagcaccggcuaacuccgugccag
cagccgcgguaauacggagggugcaagcguuaaucggaauuacugggcgu
aaagcgcacgcaggcgguuuguuaagucagaugugaaauccccgggcuca
accugggaacugcaucugauacuggcaagcuugagucucguagagggggg
uagaauuccagguguagcggugaaaugcguagagaucuggaggaauaccg
guggcgaaggcggcccccuggacgaagacugacgcucaggugcgaaagcg
uggggagcaaacaggauuagauacccugguaguccacgccguaaacgaug
ucgacuuggagguugugccggcguggcuuccggagcuaacgcguuaaguc
gaccgccuggggaguacggccgcaagguuaaaacucaaaugaauugacgg
gggcccgcacaagcgguggagcaugugguuuaauucgaugcaacgcgaag
aaccuuaccuggucuugacauccacggaaguuuucagagaugagaaugug
ccgaaccgugagacaggugcugcauggcugucgucagcucguguugugaa
auguuggguuaagucccgcaacgagcgcaacccuuauccuuuguugccag
cgguccggccgggaacucaaaggagacugccagugauaaacuggaggaag
guggggaugacgucaagucaucauggcccuuacgaccagggcuacacacg
ugcuacaauggcgcauacaaagagaagcgaccucgcgagagcaagcggac
cucauaaagugcgucguaguccggauuggagucugcaacucgacuccaug
aagucggaaucgcuaguaaucguggaucagaaugccacggugaauacguu
cccgggccuuguacacaccgcccgucacaccaugggaguggguugcaaaa
gaaguagguagcuuaaccuucgggagggcgcuuaccacuuugugauucau
gacuggggugaagucguaacaagguaaccguaggggaaccugcgguugga
uca
.......<<<<..[.((((.>>>>.<<<<.<<<<<..<<<<<<<<.....
<<<.<<<..<<<..<<.<...<<<<<<.>>>.>>>.>..>>>>>......
<<.......<<<<<<<..<<...<<<<<<<.<.<<.....<<<<<.....
.>>>>>......>>.>.....<<<....>>>....<<<<<<.>>>>>>.>
>>>>>>..>>.>>>>>>><<<....<<<..<<<<<<<.........>>>>
>>>>>>......>>>..<<<<<<<<....>>>>...>>>>.>>.<<<<<.
<.........>>>>>>.<<<<....>>>>...>>>>>>.........<<<
....<<<<....>>>>..>>>..>>.>>>>>>..<<<<......<<<<<.
.>>>>>.....>>>>...<.<<<<<......<.<<<<<<<<.......>>
>>>>>>.>........>>>>>....>..<<<<<(((...<<<<<.....<
<.)))>>.......>>>>>>>>>>..>>>>>>>>>..........<<<((
.....<<<<...<<<.<<<<<<<.<<<<<<<<<<......<<<<<<....
.>>>>>>....>>>>>>>>..>>>>>>>>>...<<<<<<<<...<<<<<<
<....<<<<<<<<...<<<......>>>......>>>>>>>>........
...<<....>>.>>>>>>>..>>>>.>>>>...>>>...>>>>....<<<
<<<...<<...<<<<.<.....>.>>>>...>>>>>>>>..........<
<<<<<.<<<<<<<<<<<<..>>>>>>>>>>>>..<<..))>>.....>>>
>>>.>>>.<<<......<<<<....>>>>....>>>..)))).]<<<<<.
<<<<<<<.<<.<<<<<<..<<<<<<<<<<......<<........>>...
.......<<<<<<<......<<<<<<<..<<<<<<<....>>>>>>>...
.....>>>>>.>>.<<<.<<<..<<<<<<.......<<<<<<<<<....>
>>..<<<<......>>>>..>>>>>>.....<<<<.<<<<<<<...<<..
<<<.....>>>>>....>>>>>>>.....<<<<<.....>>>>>......
..>>>>.........>>>...>>>>>>>>>...>>>>>>>...>>.>>>>
>>>>.....<<<<<<<.....<<<..<<...<<<....>>>...>>....
>>>.....>>>>>>>......<....<<<<<<<........>>>>>>>..
..>.....>>>>>>....<<<<<<<.........>>>>>>>......>>.
..>>>>>>>>>>.>>....<..<<.<.<<<<.<<<..<<<<<<<<<<<<.
...<<<<<<.<<<<..<<....>>.>>>>>>>>>>...>>>>>>>>>>>>
..>>>.>>>>..>.>>...>.....<<<<<<<<<....>>>>>>>>>...
...
Receptor-Ligand Complex Structure
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PDB8phj Ribosomal stalk-captured CARF-RelE ribonuclease inhibits translation following CRISPR signaling
Resolution3.67 Å
Binding residue
(original residue number in PDB)		H22 N28 N29 T33 Q38 G39 N40 A41 W44 T46 G48 R53 G54 K57 K87 P115 I116 H118 X119 G120 C121 R122 K125 R127 R128
Binding residue
(residue number reindexed from 1)		H10 N16 N17 T21 Q26 G27 N28 A29 W32 T34 G36 R41 G42 K45 K75 P103 I104 H106 X107 G108 C109 R110 K113 R115 R116
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
GO:0005515 protein binding
GO:0019843 rRNA binding
GO:0070181 small ribosomal subunit rRNA binding
Biological Process
GO:0002181 cytoplasmic translation
GO:0006412 translation
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005840 ribosome
GO:0022627 cytosolic small ribosomal subunit
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:8phj, PDBe:8phj, PDBj:8phj
PDBsum8phj
PubMed38033086
UniProtP0A7R9|RS11_ECOLI Small ribosomal subunit protein uS11 (Gene Name=rpsK)

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