Structure of PDB 8ev3 Chain K Binding Site BS01

Receptor Information
>8ev3 Chain K (length=249) Species: 4896 (Schizosaccharomyces pombe) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
ELLGSDAPLEKVCSALLEYESKRKSLLEDEQDDIEPVWLQLATLKFIGNN
RKLIPYKIAIKNPVIPSSSEACLIVKDPQRVYKDLVNEAGLSKVVTRVIG
LSKLKAKWNSYEQKRQLRDQFDIFLADDRVIPMLPRILGKTFYQKSKVPV
PVKISKGTAEQLKREVVSAYGATYFNSAPCSSFMIKCGHVSNTSTELAEN
VESILQFVSKHIVPDGAKGIASIHLKTSQSIAIPLWNNPNLKELIASSR
Ligand information
>8ev3 Chain 6 (length=75) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
acaaucuucucaugagguguugaacgaaaauuuaaauuuaguuugaaauc
gauuggugaaauuuuaccacuuugu
........<<<..>>>.....<<<<...<<<<..>>>>..>>>>......
.......<<<..>>>..........
Receptor-Ligand Complex Structure
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PDB8ev3 Chromatin localization of nucleophosmin organizes ribosome biogenesis.
Resolution3.0 Å
Binding residue
(original residue number in PDB)		W54 Q56 A58 N65 N66 R67 K68 L69 K92 D93 L117 S118 N125 S126 Y127 E128 R131 D144 R145 I147 P148 M149 P151 R152 G155 K156 K161 S162 A194 P195 C196 S197 S198 M200 H227 S238 H240 K242 Q245 S246 I247 A248
Binding residue
(residue number reindexed from 1)		W38 Q40 A42 N49 N50 R51 K52 L53 K76 D77 L101 S102 N109 S110 Y111 E112 R115 D128 R129 I131 P132 M133 P135 R136 G139 K140 K145 S146 A178 P179 C180 S181 S182 M184 H211 S222 H224 K226 Q229 S230 I231 A232
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003674 molecular_function
GO:0003723 RNA binding
Biological Process
GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0006364 rRNA processing
GO:0042254 ribosome biogenesis
GO:1902626 assembly of large subunit precursor of preribosome
Cellular Component
GO:0005634 nucleus
GO:0005730 nucleolus
GO:1990904 ribonucleoprotein complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8ev3, PDBe:8ev3, PDBj:8ev3
PDBsum8ev3
PubMed36423630
UniProtQ9UT32|RL1DB_SCHPO Putative ribosome biogenesis protein C8F11.04 (Gene Name=SPAC8F11.04)

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