Structure of PDB 8d8k Chain K Binding Site BS01

Receptor Information

>8d8k Chain K (length=141) Species: 4932 (Saccharomyces cerevisiae)

KEEVVKYILHGKFTKNNTHLTFSSVVEDKNTYNDTMLYYLNLPQKVKISL
STGCLGFRKAARGEYEAAFQTSGRMFELIKEKNMLNKDIEVVMDDFGKGR
AAFISALVGKEGASVVKKVVKISDATKLKFGGVRSPKMRRL

Ligand information

>8d8k Chain a (length=1538)

uuuuauauauauauaauaaggaaaaguauuuauaagaauaugauguuggu
ucagauuaagcgcuaaauaaggacaugacacaugcgaaucauacguuuau
uauugagauaauaaauaugugguguaaacgugaguaauuuuauuaggaau
uaaugaacuauagaauaagcuaaauacuuaauauuauauaaaaauaauuu
auauaauaaaaaggauauauauauauauauuuaucuauagucaagccaau
aaugguuuagguaguagguuuauuaagaguuaaaccuagccaacgaucca
uaaucgauaaugaaaguuagaacgaucacguugacucugaaauauaguca
auaucuauaagauacagcagugaggaauauuggacaaugaucgaaagauu
gauccaguuacuuauuaggaugauauauauauauauauaaauugauuaaa
aauaaaauccauaaauaauuaaaauaaugauauuaauuaccauauauuua
uauggauauauauauauuuuaauaguccugacuaauauuugugccagcag
ucgcgguaacacaaagagggcgagcguuaaucauaaugguuuaaaggauc
cguagaaugaauuauauauaauuuagaguuaauaaaauauaauuaaagaa
uuauaauaguaaagaugaaauaauaauaauaauuauaagacuaauauaug
ugaaaauauuaauuaaauauuaacugacauugagggauuaaaacuagagu
agcgaaacggauucgauacccguguaguucuaguaguaaacuaugaauac
aauuauuuauaauauauauauaaauaauaaaugaaaaugaaaguauucca
ccugaagaguacguuagcaauaaugaaacucaaaacaauagacgguuaca
gacuuaagcaguggagcauguuauuuaauucgauaauccacgacuaaccu
uaccauauuuugaauauuauaauaauuauaauuauuauauuacaggcguu
acauuguugucuuuaguucgugcugcaaaguuuuagauuaaguucauaaa
cgaacaaaacuccauauauauaauuuuaauuauauauaauuuuauauuau
uuauuaauauaaagaaaggaauuaagacaaaucauaaugauccuuauaau
auggguaauagacgugcuauaauaaaaugauaauaaaauuauauaaaaua
uauuuaauuauauuuaauuaauaauauaaaacauuuuaauuuuuaauaua
uuuuuuuauuauaauaugaauuauaaucugaaauucgauuauaugaaaaa
agaauugcuaguaauacguaaauuaguauguuacggugaauauucuaacu
guuucgcacuaaucacucaucacgcguugaaacauauuauuaucuuauua
uuuauauaauauuuuuuaauaaauauuauuaauuuauauuuauuuauauc
agaaauaauaugaauuaaugcgaaguugaaauacaguuaccguaggggaa
ccugcggugggcuuauaaauaucuuaaauauucuuaca

..<<<<<<..>>>>>>...................<<<<..[.((((.>>
>>.<<<<.<<<<<..<<<<<<<<.....<<<.<<<..<<<..<<<<<<<<
<<<<..>>>>>>>>>>..>>>>>.....<<<........<<<<<.<<...
...<..<<<<<<<<.<<<<.......>>>>...<<<<<<<<<.....>>>
>>>>>>......<<<<<<<<<..>>>>>>>>>.>>>>>>>>.>..>>>>>
>><<<....<<<..<<<<<<<<........>>>>>>>>>>>......>>>
..<<<<.<<<<....>>>>...>>>>.>>><<<<<<.........>>>>>
><<<<.....>>>>..>>>>>>.........<<<....<<<<....>>>>
..>>>..>>.>>>>>>.<<<<..<<<<<<....>>>>>>..<<......>
>.....>>>>..<<<<<<<<..............>>>>><<<<<<<..>>
>>>>>.<<<<..>>>>.>>>....<<<<<(((.....<<<<.....<<.)
))>>.......>>>>.>>>>>..>>>>>>>>>.....<<<((.....<<<
<...<.<<.<<<<<<..>>>>>>...<<<<<<<<.....<<<<<<<<<..
<<<<<<<....<...........>.......>>>>>>>..>>.......<
<....>>.>>>>>>>..>>>>>>>>...>>>...>>>>....<<<<<<..
.<<...<<<<.<.....>.>>>>...>>>>>>>>..........<<<<<<
.<<<<<<<<<<<<..>>.>>>>>>>>>>..<<..))>>....>>>>>>.>
>>.<<.......<<<<....>>>>.....>>..)))).]<<.<<...<<<
<......<<<<<..<<<<<<<<<<..........................
..<<<<<<<.....<<.<<<<<<<<<<..>>>>>>>>>>.>>.<<<.<<.
.<<<<<<<<<<<<..<<<<<<<<<....>>>....<<......>>....>
>>>>>.....<<<.<<<<<<<<........>>>>>>>>..<<<<<<<<<.
....>>>>>>>>>....>>>...>>>>>>>....>>>>>>>>>>...>>>
>>>>...>>.>>>>>>>>.....<<<<<<........<<<..<<..<<<<
<<......>>>>>>..>>....>>>......>>>>>>......<<<<<..
......>>>>>.....<....<<<<<<<........>>>>>>>....>..
...>>>>>.....<<.<<<<<.........>>>>>>>...........>>
>>..>>..>>....<.<<<.<.<<<<<<<<..<<<<<<<<<.<<<...<<
<..<<<.<<<<<...<<<<<<<...>>>>>>>...>>>>>>>>..>>>..
>>>>>>>>>>>>..>>>>>>>>..>.>>.>.>.....<<<<<<<<<....
>>>>>>>>>.............................

Receptor-Ligand Complex Structure

Structure summary

• PDB: 8d8k Principles of mitoribosomal small subunit assembly in eukaryotes.
• Resolution: 3.13 Å
• Binding residue (original residue number in PDB): H79 K81 K84 N85 N86 H88 N117 Q120 V122 G129 C130 K135 A136 R138 K203 L204 K205 F206 G207 V209 R210 K213 R215 R216 L217
• Binding residue (residue number reindexed from 1): H10 K12 K15 N16 N17 H19 N41 Q44 V46 G53 C54 K59 A60 R62 K127 L128 K129 F130 G131 V133 R134 K137 R139 R140 L141

Gene Ontology

Molecular Function

• GO:0003735 structural constituent of ribosome

Biological Process

• GO:0006412 translation
• GO:0032543 mitochondrial translation

Cellular Component

• GO:0005739 mitochondrion
• GO:0005743 mitochondrial inner membrane
• GO:0005763 mitochondrial small ribosomal subunit
• GO:0005840 ribosome
• GO:1990904 ribonucleoprotein complex

External links

• PDB: RCSB:8d8k, PDBe:8d8k, PDBj:8d8k
• PDBsum: 8d8k
• PubMed: 36482135
• UniProt: P42847|RT18_YEAST Small ribosomal subunit protein uS11m (Gene Name=MRPS18)