Structure of PDB 7xyg Chain K Binding Site BS01

Receptor Information
>7xyg Chain K (length=650) Species: 284812 (Schizosaccharomyces pombe 972h-) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
IDTAALKEEVLKYMNRCSTQDLADMTGCTLAEAEFVAKRPFPDLESALVV
KQPRPVIPKTPLGPRLVGICMEIMRGYFVVDALIRQCEQLGGKIQRGIEA
WGLSNTATSDEGETSLVNFDQKSFGTPANSSFITTPPASFSPDIKLQDYQ
IIGINWLYLLYELKLAGILADEMGLGKTCQTIAFFSLLMDKNINGPHLVI
APASTMENWLREFAKFCPKLKIELYYGSQVEREEIRERINSNKDSYNVLT
TYRLAATSKADRLFLRNQKFNVCVYDEGHYLKNRASERYRHLMSIPADFR
VLLTGTPLQNNLKELISLLAFILPHVFDYGLKSLDVIFTMKKSPESDFER
ALLSEQRVSRAKAPFVLRRKKSQVLKTRIIEFCEFSEEERRRYDDFASKQ
SVNSLLVMKTNLDTNANLAKKKSTAGFVLVQLRKLADHPMLFRIHYKDDI
LRQMAKAIMNEPQYKKANELYIFEDMQYMSDIELHNLCCKFPSINSFQLK
DEPWMDATKVRKLKKLLTNAVENGDRVVLFSQFTQVLDILQLVMKSLNLK
FLRFDGSTQVDFRQDLIDQFYADESINVFLLSTKAGGFGINLACANMVIL
YDVSFNPFDDLQAEDRAHRVGQKKEVTVYKFVVKDTIEEHIQRLANAKIA
Ligand information
>7xyg Chain J (length=146) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
acaggatgtatatatctgacacgtgcctggagactagggagtaatcccct
tggcggttaaaacgcgggggacagcgcgtacgtgcgtttaagcggtgcta
gagctgtctacgaccaattgagcggcctcggcaccgggattctcca
Receptor-Ligand Complex Structure
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PDB7xyg Cryo-EM structure of Fft3-nucleosome complex with Fft3 bound to SHL+3 position of the nucleosome (Class II Fft3-nucleosome complex)
Resolution4.2 Å
Binding residue
(original residue number in PDB)		Q470 R495 L496
Binding residue
(residue number reindexed from 1)		Q229 R253 L254
Enzymatic activity
Enzyme Commision number 3.6.4.12: DNA helicase.
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003682 chromatin binding
GO:0003684 damaged DNA binding
GO:0004386 helicase activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0008094 ATP-dependent activity, acting on DNA
GO:0016787 hydrolase activity
GO:0016887 ATP hydrolysis activity
GO:0140658 ATP-dependent chromatin remodeler activity
GO:0140665 ATP-dependent H3-H4 histone complex chaperone activity
GO:0140713 histone chaperone activity
Biological Process
GO:0006325 chromatin organization
GO:0006338 chromatin remodeling
GO:0031297 replication fork processing
GO:0140673 transcription elongation-coupled chromatin remodeling
GO:0140698 attachment of telomeric heterochromatin to nuclear envelope
GO:0140861 DNA repair-dependent chromatin remodeling
Cellular Component
GO:0000785 chromatin
GO:0000792 heterochromatin
GO:0005634 nucleus
GO:0005694 chromosome
GO:0032991 protein-containing complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7xyg, PDBe:7xyg, PDBj:7xyg
PDBsum7xyg
PubMed
UniProtO42861|FFT3_SCHPO ATP-dependent helicase fft3 (Gene Name=fft3)

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