Structure of PDB 7tqy Chain K Binding Site BS01

Receptor Information
>7tqy Chain K (length=365) Species: 5476 (Candida albicans) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KQSSISVAVRVRPFTEAESNRLVKIDNLRKIINVVDDRMLIFDPPETNPL
TKMQRNAFPNSFKGSRIREHRFVFDRLFDEDCTQDQVYRNTTQPLLDSVL
DGYNATVFAYGATGCGKTHTISGTPEDPGVIFLTMKELYNRIEELKDTKI
IDISLSYLEIYNETIRDLLNPMTQCKNLVIREDANNKISVSNLSRHRPNS
VEEVMQLILEGNKNRTCSPTEANATSSRSHAVLQINVIQKDRTGDITEEH
TFATLSIIDLAGSERAAATKNRGARLNEGANINKSLLALGNCINALCDPR
RRNHVPYRDSKLTRLLKFSLGGNCKTVMIVCVSPSSQHYDETLNTLKYAD
RAKEIKTKLIRNQHN
Ligand information
Ligand IDAF3
InChIInChI=1S/Al.3FH/h;3*1H/q+3;;;/p-3
InChIKeyKLZUFWVZNOTSEM-UHFFFAOYSA-K
SMILES
SoftwareSMILES
ACDLabs 10.04
CACTVS 3.341
OpenEye OEToolkits 1.5.0		F[Al](F)F
FormulaAl F3
NameALUMINUM FLUORIDE
ChEMBL
DrugBank
ZINC
PDB chain7tqy Chain K Residue 800 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB7tqy Kinesin-8-specific loop-2 controls the dual activities of the motor domain according to tubulin protofilament shape.
Resolution2.6 Å
Binding residue
(original residue number in PDB)		T187 S300 S301 G336
Binding residue
(residue number reindexed from 1)		T113 S226 S227 G262
Annotation score1
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003777 microtubule motor activity
GO:0005524 ATP binding
GO:0008017 microtubule binding
Biological Process
GO:0007018 microtubule-based movement

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:7tqy, PDBe:7tqy, PDBj:7tqy
PDBsum7tqy
PubMed35859148
UniProtA0A1D8PKA4

[Back to BioLiP]