Structure of PDB 7pio Chain K Binding Site BS01

Receptor Information
>7pio Chain K (length=136) Species: 272634 (Mycoplasmoides pneumoniae M129) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
ATIAQLIRKPRKKKKVKSKSPALHYNLNLLNKKVTNVYSPLKRGVCTRVG
TMTPKKPNSALRKYAKVRLTNGFEVLTYIPGEGHNLQEHSVTLLRGGRVK
DLPGVRYHIVRGTLDTVGVEKRRQQRSAYGAKKPKA
Ligand information
>7pio Chain 5 (length=1493) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
ucugagaguuugauccuggcucaggauuaacgcuggcggcaugccuaaua
caugcaagucgaucgaaaguaguaauacuuuagaggcgaacgggugagua
acacguauccaaucuaccuuauaaugggggauaacuaguugaaagacuag
cuaauaccgcauaagaacuuugguucgaaucaaaguugaaaggaccugca
aggguucguuauuugaugagggugcgccauaucagcuaguugguggggua
acggccuaccaaggcaaugacguguagcuaugcugagaaguagaauagcc
acaaugggacugagacacggcccauacuccuacgggaggcagcaguaggg
aauuuuucacaaugagcgaaagcuugauggagcaaugccgcgugaacgau
gaaggucuuuaagauuguaaaguucuuuuauuugggaagaaugacuuuag
cagguaauggcuagaguuugacuguaccauuuugaauaagugacgacuaa
cuaugugccagcagucgcgguaauacauaggucgcaagcguuauccggau
uuauugggcguaaagcaagcgcaggcggauugaaaagucugguguuaaag
gcagcugcuuaacaguuguaugcauuggaaacuauuaaucuagagugugg
uagggaguuuuggaauuucauguggagcggugaaaugcguagauauauga
aggaacaccaguggcgaaggcgaaaacuuaggccauuacugacgcuuagg
cuugaaaguguggggagcaaauaggauuagauacccuaguaguccacacc
guaaacgauagauacuagcugucggggcgauccccucgguagugaaguua
acacauuaaguaucucgccuggguaguacauucgcaagaaugaaacucaa
acggaauugacggggacccgcacaagugguggagcauguugcuuaauucg
acgguacacgaaaaaccuuaccuagacuugacauccuuggcaaaguuaug
gaaacauaaugccgagugacagguggugcaugguugucgucagcucgugu
cgugagauguuggguuaagucccgcaacgagcgcaacccuuaucguuagu
uacauugucuagcgagacugcuaaugcaaauuggaggaaggaagggauga
cgucaaaucaucaugccccuuaugucuagggcugcaaacgugcuacaaug
gccaauacaaacagucgccagcuuguaaaagugagcaaaucuguaaaguu
ggucucaguucggauugagggcugcaauucguccucaugaagucggaauc
acuaguaaucgcgaaucagcuaugucgcggugaauacguucucgggucuu
guacacaccgcccgucaaacuaugaaagcugguaauauuuaaaaacgugu
ugcuaaccauuaggaagcgcaugucaaggauagcaccggugauuggaguu
aagucguaacaagguaccccuacgagaacguggggguggauca
.....<<<<..[.((([.>>>>.<<<<.<<<<<..<<<<<<<<......<
<.<<<..<<<..<<.<<<<<<....>>>>>>.>>>>>......<<.....
...<<<.<<<..<<...<...<<<<<.<<.....<<<<<<....>>>>>>
......>>.>.....<<<<<<<<......>>>>>>>>....<<<<<<...
.>>>>>>>>>>...>..>>>>>.>>>.<<<....<<<..<<<<<<<<...
....>>>>>>>>>>>......>>>..<<<<<<<<....>>>...>>>>>.
>>.<<<<<.<.........>>>>>>.<<<<....>>>>...>>>>>....
......<<<...<<<<<....>>>>.>>>>..>>.>>>>>>..<<<<...
....<<<.....>>>......>>>>...<...<<<.........<<<<<<
<........>>>>>>>..........>>>....>.....<<<<<(((...
<<<<<.....<<.)))>>.......>>>>>>>>>>..>>>>>>>>>....
......<<<((.....<<<<...<<<.<<<<<<..<<<<<<<<<<.....
<<<<<<<.....>>>>>>>..>>>>>>>>..>>.>>>>>>...<<<<<<<
<...<<<<<<<....<<<<<<<<<..<<<......>>>.....>>>>>>>
>>...........<<....>>.>>>>>>>..>>>>>.>>>...>>>...>
>>>....<<<<<<...<<...<<<<.........>>>>...>>>>>>>>.
.........<<<<<<..<<<<.<<<<<......>>>>>.>>>>...<<..
))>>.....>>>>>>.>>>.<<<<....<<<<<....>>>>>..>>>>..
].))).]<<<<<.<<<<<<<.<<..<<<<<..<.<<<<<<........<<
........>>..........<<<<<<<......<<<<<<.....<<<<<<
....>>>>>>..>>>>.>>.<<<.<<<..<<<<<<.......<<<<<<<<
<....>>>..<<<<......>>>>..>>>>>>.....<<<<.<<<<<<<.
........>>>>>>>.....<<<<<....>>>>>........>>>>....
.....>>>...>>>>>>>>>...>>>>>>>......>>>>>>.>.....<
<<<<<<.....<<<..<<..<<<<....>>>>..>>....>>>....>>>
>>>>...........<<<<<<<........>>>>>>>..........>>>
>>.....<<<<<<<..........>>>>>>>......>>...>>>>>>>>
>>.>>....<..<<.<.<<<<.<<<..<<<<<<..<<<<<....<<<<<.
<<<<..<<....>>.>>>>>>>>>...>>>>>..>>>>>>..>>>.>>>>
..>.>>...>.....<<<<<<<<<....>>>>>>>>>......
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7pio Visualizing translation dynamics at atomic detail inside a bacterial cell.
Resolution9.5 Å
Binding residue
(original residue number in PDB)
A2 T3 A5 Q6 R9 R12 K13 K14 K15 S19 K20 H25 N29 L30 Y39 S40 P41 L42 K43 R44 K56 K57 N59 S60 A61 L62 R63 K64 Y79 G82 E83 R96 G97 R99 V100 K101 D102 P104 R107 K122 R123 R124 Q125 Q126 R127 S128 K134 A137
Binding residue
(residue number reindexed from 1)
A1 T2 A4 Q5 R8 R11 K12 K13 K14 S18 K19 H24 N28 L29 Y38 S39 P40 L41 K42 R43 K55 K56 N58 S59 A60 L61 R62 K63 Y78 G81 E82 R95 G96 R98 V99 K100 D101 P103 R106 K121 R122 R123 Q124 Q125 R126 S127 K133 A136
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0000049 tRNA binding
GO:0003735 structural constituent of ribosome
GO:0019843 rRNA binding
Biological Process
GO:0006412 translation
Cellular Component
GO:0005840 ribosome
GO:0015935 small ribosomal subunit
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:7pio, PDBe:7pio, PDBj:7pio
PDBsum7pio
PubMed36171285
UniProtP75546|RS12_MYCPN Small ribosomal subunit protein uS12 (Gene Name=rpsL)

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