Structure of PDB 7ode Chain K Binding Site BS01

Receptor Information
>7ode Chain K (length=226) Species: 83333 (Escherichia coli K-12) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
AVVKCKPTSPGRRHVVKVVNPELHKGKPFAPLLEKNSKSGGRNNNGRITT
RHIGGGHKQAYRIVDFKRNKDGIPAVVERLEYDPNRSANIALVLYKDGER
RYILAPKGLKAGDQIQSGVDAAIKPGNTLPMRNIPVGSTVHNVEMKPGKG
GQLARSAGTYVQIVARDGAYVTLRLRSGEMRKVEADCRATLGEVGNAEHM
LRVLGKAGAARWRGVRPTVRGTAMNP
Ligand information
>7ode Chain I (length=1990) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
gguuaagcgacuaagcguacacgguggaugcccuggcagucagaggcgau
gaaggacgugcuaaucugcgauaagcgucgguaaggugauaugaaccguu
auaaccggcgauuuccgaauggggaaacccaguguguuucgacacacuau
cauuaacugaauccauagguuaaugaggcgaaccgggggaacugaucuaa
guaccccgaggaaaagaaaucaaccgagauucccccaguagcggagcgaa
cggggagcagcccagagccugaaucaguguguguguuaguggaagcgucu
ggaaaggcgcgcgauacagggugacagccccguacacaaaaaugcacaug
cugugagcucgaugaguagggcgggacauccugucugaauagggggccau
ccuccaaggcuaaauacuccugacugaccgauagugaaccaguaccguga
gggaaaggcgaaaagaaccccggcgaggggagugaaaaagaaccugaaac
cguguacguacaagcagugggagcacgcaggcgugugacugcguaccuuu
uguauaaugggucagcgacuuauauucuguagcaagguuaaccgaauagg
ggagccgaaguugcaggguauagacccgaaacccggugaucuagccaugg
gcagguugaagguuggguaacacuaacuggaggaccgaaccgacuaaugu
ugaaaaauuagcggaugacuuguggcugggggugaaaggccaaucaaacc
gggagauagugguucuccccgaaagcuaguagcgccucgugaauucaucu
ccgcggagaauguuaucacgggagacacacggcgggugcaaguccgucgu
gaagagggaaacaacccagaccgccagcuaaggucccaaagucaugguua
agugggauguaacggggcuaaaccaugcaccgaagcugcggcagcgacgc
gcguuguuggguaggggagcguucuguaagccugcgaaggugugcuguga
ggcaugcuggagguaucagaagugcgaaugcugacauaaguaacgauaaa
gcgggugaaaagcccgcucgccggaagaccaaggguuccuguccaacguu
aaucggggcagggugagucgaccccuaaggcgaggccgaaaggcguaguc
gaugggaaacagguuaauauuccuguacuugguguuacugcgaagggggg
acggagaaggcuauguuggccgggcgacgguugucccgguuuaagcgugu
aggcugguuuuccaggcaaauccggaaaaucaaggcugaggcgugaugac
gaggcacuggugcugaagcaacaaaugcccugcuuccaggaaaagccucu
aagcacagguaacaucaaaucguaccccaaaccgacacagguggucaggu
agagaauaccaaggcgcuugagagaacucgggugaaggaacuaggcaaaa
uggugccguaacuucgggagaaggcacgcugauauguaggugaggucccc
gcggauggagcugaaaucagucgaagauaccagcuggcugcaacuguuua
uuaaaaacacagcacugugcaaacacgaaaguggacguauacggugugac
gccuuggcguaaugauggccaggcugucuccacccgagacucagugaaau
ugaacucgcugugaugcaguguacccgcggcaagaggaguugacccguau
ccggguugcucccuaucugccgugggcgcuggagaacugaggggggcugc
uccuaguacgagaggaccggaguggacgcaucacugguguucggguuguc
augccaauggcacugcccgguagcuaaaugcggaagagauaagugcgcac
gaacuugccccgagaugaguucucccugacccuuuaaggguccugaagga
acguugaagacgacgacguugauaggccggguguguaagcgcagcgaugc
guugagcuaaccgguacuaaugaaccgugaggcuuaaccu
<<<<<<<<......<<<<<<<<<<<.....<<..<<<<<<<<<<<<<...
...<<<<<<....(((.>>>.....<<<<<<<..<<<)))....>>>...
...>>>>>>>...>>>....<<<....>>><<<<<<<....>>>>>>>.<
<<<<<<<<.........>>>>>>>>>.>>...<<<<<<.....<..>...
...>>>>>.>...<.....<<....>>..<<<<<<.....<<...>>...
.>>>>>>..<<<..<<<<......<<<<<<<<<<<<<.<<<...<<<<<.
.....>>>>>((......<<<.....))>>>...>>>...>>>>>>>>>>
>>>...>>>>........<<<<<<<<..>>>>>>>>.....<<<<.....
.>>>>..>>>....>.>>.>>>>>>>.>>...............<<....
>>....>>.........<<<<.....>>>>..................>>
>>>>>>>>>.......<<<<..<<<<<<..>>>>>>..>>>>...<.<<.
.....>>.>.<<<<<<<..<<<<<<<<<<<<<<..<<<...<<.....>>
...>>>...>>>>>>>>>>>>>>.<<.....<<<<<<.....<<<<<<<<
<..<<<....<<<<<<......>>>>>>.....>>>...<<<.<<<<<..
......>>>>>>>>....>>>>>>>>>...<<<.....>>>......>>>
>>>.......>>..<<<<<<....<<<<.>>>>.<<<<<<<<...<<<<<
<<..>>>>.>>>...>>>>>>>.>...<<<<<<<<<......>>>>>>>>
>....<<<......>>>...<<<<.<<<...<<<(((.....<<<<<<..
.............))).....>>>>>>.>>>...>>>>>>><<<<<<<<.
.>>>>>>>>....>>>>>><.<<<<<...<<<......<<<<<<<<....
>>>>>>>>...>>>..>>>>>..>....>>>>>>><......<<.....<
<<<<<.......>>>>>><<<<....<<<<<.<<...<<<<<<...<<..
...>>.>>>>>>....((<<<.<<<...<<<...<<<....>>>...>>>
...>>>..<<<<<........>>>>>))<<<<<<<<<<<<<...<<<<..
..<<<<..<<<..<<<<<<<<<<<....(((...>>>>>><<..<<<<..
.<<<<<<<<<<<<.<<.....>>>>>>>>>>..>>>>...>>>>...>><
..<<<<<..>>>>>...>>>>>>...>>>...>>>>.........>>>>.
..>>...>>>>>>>>>>>.>>>..>>.....<<......>>>>>>>.<<<
<.....>>>>..>>>>..<<<<....<<<<<<<<.<<.............
..<<<<<...............>>>>><<<<<<.....<<<...<<<<..
..>>>>...>>>...>>>>>>............<<<<<<<<<..<<<...
......>>>..<<<<<<<.....<<<....>>>.......>>>>>>>.<<
<<<..>>>>>..>>.>>>>>>>.....>>.>>>>>>>>.>>>>>>.....
>.....<<<<<.....>>>>>..<<<<<<<<.<<<<<..<.<<<<<<...
.>>>>>>>...>>..>>>>>>>>>>>....<<<<<<<...<<<<..<<<<
<<<...............>>>>>>>.<<<<<...<<<<...<<<<<<<<<
<<))).>>>>>>..>>>>>...>>>>.>>>>>...<<<....<<<<>>>>
...>>>.>>>>.......>>>>>>>..<<<<<.....>>>>><....<<.
.<<<<<.......>>>>>....<<<<<<<<..<<....<<<<<....>>>
>>...>>...>>>>>.>>>.....>>..>..>>>>>>>>.
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7ode Structural Consequences of Deproteinating the 50S Ribosome.
Resolution2.84 Å
Binding residue
(original residue number in PDB)
K7 P8 T9 S10 P11 G12 R13 R14 H15 K18 E35 K36 K39 S40 R43 N44 N45 N46 G47 R48 I49 T50 T51 R52 G56 H58 K59 Q60 A61 Y62 R63 I74 Y83 P85 N86 R87 D98 G99 E100 R101 M146 K147 K150 Q153 L154 A155 R156 S157 A158 G159 T160 L176 R177 S178 E180 R182 E185 A198 H200 M201 L205 G206 K207 A208 G209 R212 W213 R214 R217 P218 T219 V220 R221 T223 A224 M225
Binding residue
(residue number reindexed from 1)
K6 P7 T8 S9 P10 G11 R12 R13 H14 K17 E34 K35 K38 S39 R42 N43 N44 N45 G46 R47 I48 T49 T50 R51 G55 H57 K58 Q59 A60 Y61 R62 I73 Y82 P84 N85 R86 D97 G98 E99 R100 M145 K146 K149 Q152 L153 A154 R155 S156 A157 G158 T159 L175 R176 S177 E179 R181 E184 A197 H199 M200 L204 G205 K206 A207 G208 R211 W212 R213 R216 P217 T218 V219 R220 T222 A223 M224
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003735 structural constituent of ribosome
GO:0005515 protein binding
GO:0008270 zinc ion binding
GO:0016740 transferase activity
GO:0019843 rRNA binding
Biological Process
GO:0000027 ribosomal large subunit assembly
GO:0002181 cytoplasmic translation
GO:0006412 translation
GO:0032297 negative regulation of DNA-templated DNA replication initiation
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005840 ribosome
GO:0015934 large ribosomal subunit
GO:0022625 cytosolic large ribosomal subunit
GO:1990082 DnaA-L2 complex
GO:1990904 ribonucleoprotein complex

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Molecular Function

View graph for
Biological Process

View graph for
Cellular Component
External links
PDB RCSB:7ode, PDBe:7ode, PDBj:7ode
PDBsum7ode
PubMed36358955
UniProtP60422|RL2_ECOLI Large ribosomal subunit protein uL2 (Gene Name=rplB)

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