Structure of PDB 7lc9 Chain K Binding Site BS01

Receptor Information
>7lc9 Chain K (length=38) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
EQVTNVGGAVVTGVTAVAQKTVEGAGSIAAATGFVKKD
Ligand information
>7lc9 Chain L (length=29) Species: 9606 (Homo sapiens) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
GGAVVTGVTAVAQKTVEGAGSIAAATGFV
Receptor-Ligand Complex Structure
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PDB7lc9 The N terminus of alpha-synuclein dictates fibril formation.
Resolution3.2 Å
Binding residue
(original residue number in PDB)		G67 G68 A69 V70 V71 T72 G73 V74 T75 A76 V77 A78 Q79 K80 T81 V82 E83 G84 A85 G86 S87 I88 A89 A90 A91 T92 G93 F94 V95
Binding residue
(residue number reindexed from 1)		G7 G8 A9 V10 V11 T12 G13 V14 T15 A16 V17 A18 Q19 K20 T21 V22 E23 G24 A25 G26 S27 I28 A29 A30 A31 T32 G33 F34 V35
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0014059 regulation of dopamine secretion
Cellular Component
GO:0005737 cytoplasm

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Biological Process
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Cellular Component
External links
PDB RCSB:7lc9, PDBe:7lc9, PDBj:7lc9
PDBsum7lc9
PubMed34452994
UniProtP37840|SYUA_HUMAN Alpha-synuclein (Gene Name=SNCA)

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