Structure of PDB 7b5m Chain K Binding Site BS01

Receptor Information
>7b5m Chain K (length=69) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
QIYYSDKYDDEEFEYRHVMLPKDIAKLVPKTHLMSESEWRNLGVQQSQGW
VHYMIHEPEPHILLFRRPL
Ligand information
Receptor-Ligand Complex Structure
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PDB7b5m Ubiquitin ligation to F-box protein targets by SCF-RBR E3-E3 super-assembly.
Resolution3.91 Å
Binding residue
(original residue number in PDB)		Y8 S9 R20 R44 Q49 Q50 S51 W54
Binding residue
(residue number reindexed from 1)		Y4 S5 R16 R40 Q45 Q46 S47 W50
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005515 protein binding
GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity
GO:0019901 protein kinase binding
GO:0042393 histone binding
GO:0043130 ubiquitin binding
GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity
Biological Process
GO:0006355 regulation of DNA-templated transcription
GO:0007346 regulation of mitotic cell cycle
GO:0044772 mitotic cell cycle phase transition
GO:0048144 fibroblast proliferation
GO:0051301 cell division
Cellular Component
GO:0000307 cyclin-dependent protein kinase holoenzyme complex
GO:0005654 nucleoplasm
GO:0019005 SCF ubiquitin ligase complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7b5m, PDBe:7b5m, PDBj:7b5m
PDBsum7b5m
PubMed33536622
UniProtP61024|CKS1_HUMAN Cyclin-dependent kinases regulatory subunit 1 (Gene Name=CKS1B)

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