Structure of PDB 7at8 Chain K Binding Site BS01

Receptor Information
>7at8 Chain K (length=93) Species: 8355 (Xenopus laevis) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
TRKESYAIYVYKVLKQVHPDTGISSKAMSIMNSFVNDVFERIAGEASRLA
HYNKRSTITSREIQTAVRLLLPGELAKHAVSEGTKAVTKYTSA
Ligand information
>7at8 Chain T (length=156) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
tcatactggagaatcccggtgccgaggccgctcaattggtcgtagacagc
tctagcaccgcttaaacgcacgtacgcgctgtcccccgcgttttaaccgc
caaggggattactccctagtctccaggcacgtgtcagatatatatacatc
ctgtat
Receptor-Ligand Complex Structure
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PDB7at8 Structural basis for PRC2 decoding of active histone methylation marks H3K36me2/3.
Resolution4.4 Å
Binding residue
(original residue number in PDB)		R30 I36 Y37
Binding residue
(residue number reindexed from 1)		R2 I8 Y9
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0005515 protein binding
GO:0030527 structural constituent of chromatin
GO:0046982 protein heterodimerization activity
Cellular Component
GO:0000786 nucleosome
GO:0005634 nucleus
GO:0005694 chromosome

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Molecular Function
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Cellular Component
External links
PDB RCSB:7at8, PDBe:7at8, PDBj:7at8
PDBsum7at8
PubMed33211010
UniProtP02281|H2B11_XENLA Histone H2B 1.1

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