Structure of PDB 7afl Chain K Binding Site BS01

Receptor Information
>7afl Chain K (length=117) Species: 562 (Escherichia coli) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
RKQVSDGVAHIHASFNNTIVTITDRQGNALGWATAGGSGFRGSRKSTPFA
AQVAAERCADAVKEYGIKNLEVMVKGPGPGRESTIRALNAAGFRITNITD
VTPIPHNGCRPPKKRRV
Ligand information
>7afl Chain A (length=1054) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
aaauugaagaguuugaucauggcucagauugaacgcuggcggcaggccua
acacaugcaagucgaacgguaacaggaagaagcuugcuucuuugcugacg
aguggcggacgggugaguaaugucugggaaacugccugauggagggggau
aacuacuggaaacgguagcuaauaccgcauaacgucgcaagaccaaagag
ggggaccuucgggccucuugccaucggaugugcccagaugggauuagcua
guaggugggguaacggcucaccuaggcgacgaucccuagcuggucugaga
ggaugaccagccacacuggaacugagacacgguccagacuccuacgggag
gcagcaguggggaauauugcacaaugggcgcaagccugaugcagccaugc
cgcguguaugaagaaggccuucggguuguaaaguacuuucagcggggagg
aagggaguaaaguuaauaccuuugcucauugacguuacccgcagaagaag
caccggcuaacuccgugccagcagccgcgguaauacggagggugcaagcg
uuaaucggaauuacugggcguaaagcgcacgcaggcgguuuguuaaguca
gaugugaaauccccgggcucaaccugggaacugcaucugauacuggcaag
cuugagucucguagagggggguagaauuccagguguagcggugaaaugcg
uagagaucuggaggaauaccgguggcgaaggcggcccccuggacgaagac
ugacgcucaggugcgaaagcguggggagcaaacaggauuagauacccugg
uaguccacgccguaaacgaugucgacuuggagguugugcccuugaggcgu
ggcuuccggagcuaacgcguuaagucgaccgccuggggaguacggccgca
agguuaaaacucaaaugaauugacgggggcgccuuguacaccaccauggg
aguggguugcaaaagaaguagguagcuuaaccuucgggagggcgcuuacc
acuuugugauucaugacuggggugaaccguaggggaaccugcgguuggau
cacc
........<<<<..[.((((.>>>>.<<<..<<<<<..<<<<<<<<....
.<<<.<<<..<<<..<<.<...<<.<<<.<<<....>>>.>>>..>>.>.
.>>>>>......<<.......<<<<<<<..<<...<<<<<<<...<<...
..<<<<........>>>>......>>.......<<<....>>>....<<<
<<<..<<....>>>>>>>>.>>>>>>>..>>.>>>>>>><<<....<<<.
..<<<<<<.........>>>>>>.>>>......>>>..<<<<<<<<....
>>>...>>>>>.>>.<<<<<............>>>>>.<<<<....>>>>
...>>>>>>.........<<<....<<<<....>>>>..>>>..>>.>>>
>>>..<<<<.......<<<....>>>......>>>>...<.<<<<<....
..<.<<<<<<<<.......>>>>>>>>.>........>>>>>....>..<
<<<<(((...<<<<<.....<<.)))>>.......>>>>>>>>>>..>>>
>>.>>>..........<<<((.....<<<<...<<<.<<<<<<<.<<<<<
<<<<<......<<<<<<.....>>>>>>....>>>>>>>>..>>>>>>>>
>...<<<<<<<<...<<<<<<.....<<<<<<<<.....<......>...
.....>>>>>>>>...........<<....>>..>>>>>>..>>>>.>>>
>...>>>...>>>>....<<<<<<...<<...<<<<.........>>>>.
..>>>>>>>>..........<<<<<<..<<<<<<.<<<<<.....>>>>>
.>>>>>>...<<..))>>.....>>>>>>.>>>.<<<.......<<<...
.>>>.....>>>..)))).]<<<<<.<<<..>>>>>>.>>...<<.<<<.
.<<<<<<<<<<<<....<<<<<<.<<<<..<<....>>.>>>>>>>>>>.
..>>>>>>>>>>>>..>>>.>>..<<<<<<<<<....>>>>>>>>>....
....
Receptor-Ligand Complex Structure
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PDB7afl A conserved rRNA switch is central to decoding site maturation on the small ribosomal subunit.
Resolution4.2 Å
Binding residue
(original residue number in PDB)
H22 N28 N29 T33 N40 A41 L42 G43 W44 T46 G48 G49 R53 G54 S55 K57 M85 K87 P117 H118 G120 C121 R122 P123 P124 K125 R127 R128
Binding residue
(residue number reindexed from 1)
H10 N16 N17 T21 N28 A29 L30 G31 W32 T34 G36 G37 R41 G42 S43 K45 M73 K75 P105 H106 G108 C109 R110 P111 P112 K113 R115 R116
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
GO:0005515 protein binding
GO:0019843 rRNA binding
GO:0070181 small ribosomal subunit rRNA binding
Biological Process
GO:0002181 cytoplasmic translation
GO:0006412 translation
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005840 ribosome
GO:0022627 cytosolic small ribosomal subunit
GO:1990904 ribonucleoprotein complex

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:7afl, PDBe:7afl, PDBj:7afl
PDBsum7afl
PubMed34088665
UniProtP0A7R9|RS11_ECOLI Small ribosomal subunit protein uS11 (Gene Name=rpsK)

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