Structure of PDB 6wwk Chain K Binding Site BS01

Receptor Information
>6wwk Chain K (length=368) Species: 10090 (Mus musculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
LGSNSQVTVAVRVRPFSKREKTEKASQVVFTNGEEITVEHPDMKQVYSFI
YDVSFWSFDECHPGYASQTTVYETLAAPLLDRAFEGYNTCLFAYGQTGSG
KSYTMMGLNEEPGIIPRFCEDLFAQIAKKQTSEVSYHLEMSFFEVYNEKI
HDLLVCKGENGQRKQPLRAREHPVSGPYVEGLSMNVVSSYSDIQSWLELG
NKQRATAATGMNDKSSRSHSVFTLVMTQTKTEVVEGEEHDHRITSRINLV
DLAGSERCSTAHSSGQRLKEGVSINKSLLTLGKVISALSEQANGKRVFIP
YRESTLTWLLKESLGGNSKTAMIATVSPAASNIEETLSTLRYATQARLIV
NIAKVNEDMNAKLIRELK
Ligand information
Ligand IDAF3
InChIInChI=1S/Al.3FH/h;3*1H/q+3;;;/p-3
InChIKeyKLZUFWVZNOTSEM-UHFFFAOYSA-K
SMILES
SoftwareSMILES
ACDLabs 10.04
CACTVS 3.341
OpenEye OEToolkits 1.5.0		F[Al](F)F
FormulaAl F3
NameALUMINUM FLUORIDE
ChEMBL
DrugBank
ZINC
PDB chain6wwk Chain K Residue 800 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB6wwk Structural basis of mechano-chemical coupling by the mitotic kinesin KIF14.
Resolution3.0 Å
Binding residue
(original residue number in PDB)		T484 K488 N599 S602 S603 A640
Binding residue
(residue number reindexed from 1)		T97 K101 N212 S215 S216 A253
Annotation score1
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003777 microtubule motor activity
GO:0005524 ATP binding
GO:0008017 microtubule binding
Biological Process
GO:0007018 microtubule-based movement

View graph for
Molecular Function
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Biological Process
External links
PDB RCSB:6wwk, PDBe:6wwk, PDBj:6wwk
PDBsum6wwk
PubMed34131133
UniProtL0N7N1|KIF14_MOUSE Kinesin-like protein KIF14 (Gene Name=Kif14)

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