Structure of PDB 6wwh Chain K Binding Site BS01

Receptor Information
>6wwh Chain K (length=366) Species: 10090 (Mus musculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
FNSQVTVAVRVRPFSKREKTEKASQVVFTNGEEITVEHPDMKQVYSFIYD
VSFWSFDECHPGYASQTTVYETLAAPLLDRAFEGYNTCLFAYGQTGSGKS
YTMMGLNEEPGIIPRFCEDLFAQIAKKQTSEVSYHLEMSFFEVYNEKIHD
LLVCKGENGQRKQPLRAREHPVSGPYVEGLSMNVVSSYSDIQSWLELGNK
QRATAATGMNDKSSRSHSVFTLVMTQTKTEVVEGEEHDHRITSRINLVDL
AGSERCSTAHSSGQRLKEGVSINKSLLTLGKVISALSEQANGKRVFIPYR
ESTLTWLLKESLGGNSKTAMIATVSPAASNIEETLSTLRYATQARLIVNI
AKVNEDMNAKLIRELK
Ligand information
Ligand IDMG
InChIInChI=1S/Mg/q+2
InChIKeyJLVVSXFLKOJNIY-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mg+2]
CACTVS 3.341[Mg++]
FormulaMg
NameMAGNESIUM ION
ChEMBL
DrugBankDB01378
ZINC
PDB chain6wwh Chain K Residue 801 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6wwh Structural basis of mechano-chemical coupling by the mitotic kinesin KIF14.
Resolution3.8 Å
Binding residue
(original residue number in PDB)		S489 S603
Binding residue
(residue number reindexed from 1)		S100 S214
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003777 microtubule motor activity
GO:0005524 ATP binding
GO:0008017 microtubule binding
Biological Process
GO:0007018 microtubule-based movement

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Molecular Function
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Biological Process
External links
PDB RCSB:6wwh, PDBe:6wwh, PDBj:6wwh
PDBsum6wwh
PubMed34131133
UniProtL0N7N1|KIF14_MOUSE Kinesin-like protein KIF14 (Gene Name=Kif14)

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