Structure of PDB 6wwg Chain K Binding Site BS01

Receptor Information
>6wwg Chain K (length=367) Species: 10090 (Mus musculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
EFNSQVTVAVRVRPFSKREKTEKASQVVFTNGEEITVEHPDMKQVYSFIY
DVSFWSFDECHPGYASQTTVYETLAAPLLDRAFEGYNTCLFAYGQTGSGK
SYTMMGLNEEPGIIPRFCEDLFAQIAKKQTSEVSYHLEMSFFEVYNEKIH
DLLVCKGENGQRKQPLRAREHPVSGPYVEGLSMNVVSSYSDIQSWLELGN
KQRATAATGMNDKSSRSHSVFTLVMTQTKTEVVEGEEHDHRITSRINLVD
LAGSERCSTAHSSGQRLKEGVSINKSLLTLGKVISALSEQANGKRVFIPY
RESTLTWLLKESLGGNSKTAMIATVSPAASNIEETLSTLRYATQARLIVN
IAKVNEDMNAKLIRELK
Ligand information
Ligand IDAF3
InChIInChI=1S/Al.3FH/h;3*1H/q+3;;;/p-3
InChIKeyKLZUFWVZNOTSEM-UHFFFAOYSA-K
SMILES
SoftwareSMILES
ACDLabs 10.04
CACTVS 3.341
OpenEye OEToolkits 1.5.0		F[Al](F)F
FormulaAl F3
NameALUMINUM FLUORIDE
ChEMBL
DrugBank
ZINC
PDB chain6wwg Chain K Residue 800 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB6wwg Structural basis of mechano-chemical coupling by the mitotic kinesin KIF14.
Resolution2.9 Å
Binding residue
(original residue number in PDB)		S602 S603 A640 G641
Binding residue
(residue number reindexed from 1)		S214 S215 A252 G253
Annotation score1
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003777 microtubule motor activity
GO:0005524 ATP binding
GO:0008017 microtubule binding
Biological Process
GO:0007018 microtubule-based movement

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Molecular Function
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Biological Process
External links
PDB RCSB:6wwg, PDBe:6wwg, PDBj:6wwg
PDBsum6wwg
PubMed34131133
UniProtL0N7N1|KIF14_MOUSE Kinesin-like protein KIF14 (Gene Name=Kif14)

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