Structure of PDB 6vz4 Chain K Binding Site BS01

Receptor Information
>6vz4 Chain K (length=616) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
RKKERNLHLQKINSIIDFIKERQSEQWSRQERCFQFGRLGASLHNQMEKD
EQKRIERTAKQRLAALKSNLLDQTKDTRITQLLRQTNSFLDSLSEAVRAQ
QNDYYEVAHRIKEKIDKQPSILVGGTLKEYQLRGLEWMVSLYNNHLNGIL
ADEMGLGKTIQSISLITYLYEVKKDIGPFLVIVPLSTITNWTLEFEKWAP
SLNTIIYKGTPNQRHSLQHQIRVGNFDVLLTTYEYIIKDKSLLSKHDWAH
MIIDEGHRMKNAQSKLSFTISHYYRTRNRLILTGTPLQNNLPELWALLNF
VLPKIFNSAKTFEDWFNTPFLTEEETLLIIRRLHKVLRPFLLRRLKKEVE
KDLPDKVEKVIKCKLSGLQQQLYQQMLKHNNNKIMQLRKICNHPFVFDEV
EGVVNPSRGNSDLLFRVAGKFELLDRVLPKFKASGHRVLMFFQMTQVMDI
MEDFLRMKDLKYMRLDGSTKTEERTEMLNAFNAPDSDYFCFLLSTRAGGL
GLNLQTADTVIIFDTDWNPHQDLQAQDRAHRIGQKNEVRILRLITTDSVE
EVILERAMQKLDIDGKVIQAGAELDDDELNDTLARSADEKILFDKIDKER
MNQEKEDSEPLGRIRQ
Ligand information
>6vz4 Chain I (length=146) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
tcgagaatcccggtgccgaggccgctcaattggtcgtagacagctctagc
accgcttaaacgcacgtacgcgctgtcccccgcgttttaaccgccaaggg
gattactccctagtctccaggcacgtgtcagatatatacatcctga
Receptor-Ligand Complex Structure
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PDB6vz4 Structural insights into assembly and function of the RSC chromatin remodeling complex.
Resolution3.9 Å
Binding residue
(original residue number in PDB)		K603 S607 K608 L609 K755 W889 R928 K932
Binding residue
(residue number reindexed from 1)		K260 S264 K265 L266 K383 W517 R556 K560
Enzymatic activity
Enzyme Commision number 3.6.4.12: DNA helicase.
Gene Ontology
Molecular Function
GO:0005524 ATP binding
GO:0042393 histone binding
GO:0140658 ATP-dependent chromatin remodeler activity

View graph for
Molecular Function
External links
PDB RCSB:6vz4, PDBe:6vz4, PDBj:6vz4
PDBsum6vz4
PubMed33288924
UniProtP32597|STH1_YEAST Nuclear protein STH1/NPS1 (Gene Name=STH1)

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