Structure of PDB 6hum Chain K Binding Site BS01

Receptor Information
>6hum Chain K (length=206) Species: 197221 (Thermosynechococcus vestitus BP-1) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
PAILNPIARPEVPQELAENIILTSLNDVYDWARLSSLWPLMYGTACCFIE
FAAMIGSRFDFDRFGLVPRNSPRQADLIITSGTITMKMAPALVRLYEQMP
SPKYVIAMGACTITGGMFSSDSYSAVRGVDKLIPVDVYLPGCPPRPEAIM
DAIVKLRKKIANEHINERGNLAQTHRLFTAKHKMKPVPPILTGQYLNAPS
RQAPPP
Ligand information
Ligand IDSF4
InChIInChI=1S/4Fe.4S
InChIKeyLJBDFODJNLIPKO-UHFFFAOYSA-N
SMILES
SoftwareSMILES
OpenEye OEToolkits 2.0.7[S]12[Fe]3[S]4[Fe]1[S]5[Fe]2[S]3[Fe]45
CACTVS 3.385S1[Fe]S[Fe]1.S2[Fe]S[Fe]2
FormulaFe4 S4
NameIRON/SULFUR CLUSTER
ChEMBL
DrugBank
ZINC
PDB chain6hum Chain K Residue 501 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB6hum Structural adaptations of photosynthetic complex I enable ferredoxin-dependent electron transfer.
Resolution3.34 Å
Binding residue
(original residue number in PDB)		C52 C53 T89 G115 C117 C148 P149
Binding residue
(residue number reindexed from 1)		C46 C47 T83 G109 C111 C142 P143
Annotation score1
Enzymatic activity
Enzyme Commision number 7.1.1.-
Gene Ontology
Molecular Function
GO:0005506 iron ion binding
GO:0008137 NADH dehydrogenase (ubiquinone) activity
GO:0016655 oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor
GO:0046872 metal ion binding
GO:0048038 quinone binding
GO:0051536 iron-sulfur cluster binding
GO:0051539 4 iron, 4 sulfur cluster binding
Biological Process
GO:0009060 aerobic respiration
GO:0015990 electron transport coupled proton transport
GO:0019684 photosynthesis, light reaction
Cellular Component
GO:0009579 thylakoid
GO:0016020 membrane
GO:0031676 plasma membrane-derived thylakoid membrane
GO:0042651 thylakoid membrane

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:6hum, PDBe:6hum, PDBj:6hum
PDBsum6hum
PubMed30573545
UniProtQ8DKZ4|NDHK_THEVB NAD(P)H-quinone oxidoreductase subunit K (Gene Name=ndhK)

[Back to BioLiP]