Structure of PDB 6gc7 Chain K Binding Site BS01

Receptor Information
>6gc7 Chain K (length=122) Species: 83333 (Escherichia coli K-12) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MIQEQTMLNVADNSGARRVMCIKVLGGSHRRYAGVGDIIKITIKEAIPRG
KVKKGDVLKAVVVRTKKGVRRPDGSVIRFDGNACVLLNNNSEQPIGTRIF
GPVTRELRSEKFMKIISLAPEV
Ligand information
>6gc7 Chain A (length=1901) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
gguuaagcgacuaagcguacacgguggaugcccuggcagucagaggcgau
gaaggacgugcuaaucugcgauaagcgucgguaaggugauaugaaccguu
auaaccggcgauuuccgaauggggaaacccaguguguuucgacacacuau
cauuaacugaauccauagguuaaugaggcgaaccgggggaacugaaacau
cuaaguaccccgaggaaaagaaaucaaccgagauucccccaguagcggcg
agcgaacggggagcagcccagagccugaaucaguguguguguuaguggaa
gcgucuggaaaggcgcgcgauacagggugacagccccguacacaaaaaug
cacaugcugugagcucgaugaguagggcgggacacgugguauccugucug
aauauggggggaccauccuccaaggcuaaauacuccugacugaccgauag
ugaaccaguaccgugagggaaaggcgaaaagaaccccggcgaggggagug
aaaaagaaccugaaaccguguacguacaagcagugggagcacgcuuaggc
gugugacugcguaccuuuuguauaaugggucagcgacuuauauucuguag
caagguuaaccgaauaggggagccgaagggaaaccgagucuuaacugggc
guuaaguugcaggguauagacccgaaacccgguggugaaaggccaaucaa
accgggagauagcugguucuccccgaaagcuauuuagguagcgccucgug
aauucaucuccggggguagagcaccaaacugcgaauaccggagaauguua
ucacgggagacacacggcgggugcuaacguccgucgugaagagggaaaca
acccagaccgccagcuaaggucccaaagucaugguuaagugggaaacgcg
gaagauguaacggggcuaaaccaugcaccgaagcugcggcagcgacgcuu
augcguuguuggguaggggagcguucuguaagccugcgaaggugugcugu
gaggcaugcuggagguaucagaagugcgaaugcugacauaaguaacgaua
aagcgggugaaaagcccgcucgccggaagaccaaggguuccuguccaacg
uuaaucggggcagggugagucgaccccuaaggcgaggccgaaaggcguag
ucgaugggaaacagguuaauauuccuguacuugguguuacugcgaagggg
ggacggagaaggcuauguuggccgggcgacgguugucccgguuuaagcgu
guaggcugguuuuccaggcaaauccggaaaaucaaggcugaggcgugaug
acgaggcacuacggugcugaagcaacaaaugcccugcuuccaggaaaagc
cucuaagcaucagguaacaucaaaucguaccccaaaccgacacagguggu
cagguagagaauaccaaggcgcuugagagaacucgggugaaggaacuagg
caaaauggugccggcacgcugauauguaggugaggucccucgcggaugga
gcugaaaucagucgaagauaccagcuggcgccaggcugucuccacccgag
acucagugaaauugaacucgcugugaagaugcaguguacccgcggcaaga
cggaaaucccuaucugccgugggcgcuggagaacugaggggggcugcucc
uaguacgagaggaccggaguggacgcaucacugguguucggguugucaug
ccaauggcacugcccgguagcuaaaugcggaagagauaagugcugaaagc
aucuaagcacgaaacuugccccgagaugaguucucccugacccuuuaagg
guccugaaggaacguugaagacgacgacguugauaggccggguguguaag
cgcagcgaugcguugagcuaaccgguacuaaugaaccgugaggcuuaacc
u
<<<<<<<<......<<<<<<<<<<<....<.<<.<<<<<<<<<<<<<...
...<<<<<<....(((.>>>.....<<<<<<<..<<<)))....>>>...
...>>>>>>>...>>>....<<<....>>><<<<<<<....>>>>>>>.<
<<<<<<<<.........>>>>>>>>>.>>...<<<<<<.....<<....>
>......>>>>>.>.........<......>..<<<<<<.....<<....
.>>....>>>>>>..<<<..<<<<......<<<<<<<<<<<<<.<<<...
<<<<<......>>>>>((......<<<.....))>>>...>>>.>..>>>
>>>>>>>>>...>>>>........<<<<<<<<.........>>>>>>>>.
.....<<<<<......>>>>>..>>>......>>.>>>>>>>.>>.....
..........<<....>>....>>.........<<<.......>>>....
.........>....>>>>>>>>>>>.......<<<<..<<<<<......>
>>>>..>>>>...<.<........>.>.<<<<<<....<<<<<<<<<<<<
<..<<<...<<.....>>...>>>...<<....>>..<<<<.....>>>>
.....>>>>>>>>>>>>>..<<.<...<<<<<<.<<.....>>.......
>>>>>>......>.>>..<<<<<<....<<<<<....>>>>>..<<<<<<
<...<<<<<<<<<......<<.......>>.......>>>>>>.>>>...
>>>>>>>.....<<<<<<<<<<......>>>>>>>>>>....<<<.....
.>>>...<<<<.<<<...<<<(((.....<<<<<<...........<..>
...........))).....>>>>>>.>>>...>>>>>>><<<.<..<...
...>..>.>>>....>>>>>><<<<<<<...<<<......<<<<<<<<..
..>>>>>>>>...>>>..>>>>>.>>.....>>>>>><......<<....
.<<<<<<.......>>>>>><<<<....<<.<<.<<...<<<<<<...<<
.....>>.>>>>>>....((<<<.<<<...<<....<<<....>>>....
>>...>>>...<<<<........>>>>.))<<<<<<<<<<<<<...<<<<
....<<<<..<<<..<<<<<<<<<<<....(((...>>>>>><<..<<<<
...<<<<<<<<<<<<.<<.....>>>>>>>>>>..>>>>...>>>>...>
><..<<<<<....>>>>>...>>>>>>...>>>...>>>>.........>
>>>...>>....>>>>>>>>>>>.>>>..>>.....<<......>>>>.>
>.<<<<.....>>>>..>>>>..<<<<....<<<<<<<<.<<........
.......<<<<..>>>><<<<<......<<<...<<<<.....>>>>...
>>>....>>>>>............<<<<..>>>>.....>>.>>>>>>>>
.>>>>>>.....>.....<<<<<........>>>>>..<<<<<<<<.<<<
.<.......>..>>>>>>>>>>>....<<<<<<<...<<<<..<<<<<<<
...............>>>>>>>.<<<<<...<<<<...<<<<<<<<<<<)
)).>>>>>>..>>>>>...>>>>.>>>>>...<<<....<<<<<......
.....>>>>>....>>>.>>>>.......>>>>>>>..<<<<<.....>>
>>>.....<<..<<<<<.......>>>>>....<<<<<<<<..<<....<
<<<<....>>>>>...>>...>>>>>.>>>.....>>.....>>>>>>>>
.
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6gc7 Structural Visualization of the Formation and Activation of the 50S Ribosomal Subunit during In Vitro Reconstitution.
Resolution4.3 Å
Binding residue
(original residue number in PDB)		M1 Q3 Q5 T6 H29 R31 Y32 K67 R70
Binding residue
(residue number reindexed from 1)		M1 Q3 Q5 T6 H29 R31 Y32 K67 R70
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
GO:0005515 protein binding
GO:0019843 rRNA binding
GO:0070180 large ribosomal subunit rRNA binding
Biological Process
GO:0002181 cytoplasmic translation
GO:0006412 translation
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005840 ribosome
GO:0015934 large ribosomal subunit
GO:0022625 cytosolic large ribosomal subunit
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:6gc7, PDBe:6gc7, PDBj:6gc7
PDBsum6gc7
PubMed29883607
UniProtP0ADY3|RL14_ECOLI Large ribosomal subunit protein uL14 (Gene Name=rplN)

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