Structure of PDB 6agb Chain K Binding Site BS01

Receptor Information
>6agb Chain K (length=128) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
NGTLLVPPPRTIANQDHFHRLNYLYQISAYQTRARQKARTDAHTPLARNY
IKSMDLISKKTKTSLLPTIKRTICKKCHRLLWTPKKLEITSDGALSVMCG
CGTVKRFNIGADPNYRTYSEREGNLLNS
Ligand information
>6agb Chain A (length=369) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
guggaacagugguaauuccuacgauuaagaaaccuguuuacagaaggauc
cccaccuaugggcggguuaucagauauuaucaggugggaaauucggugga
acacaguggagccuuguccuccggguuaaugucgcuuuuggcauuggccc
cugcuccugagagaagaaauauacuggggaaccagucuuuaccgaccguu
guuaucagaaauucacggaguucggccuaggucggacuccgaugggaacg
gcaacgguuguuccguuugacuugucgcccgcuacggcgugagcgucaag
gucuguugagugcaaucguaggacgucauuaguggcgaacccgauaccga
uuacugcugcuguuccagc
.<<<<<<<<<<<<<..<<<<<<<........<<<<<..........<<<.
<<<.<<....>>.>>>..>>>.........>>>>>[[...{{.(((((..
......<<<<<<.........<<<<<<<<<<<<<....>>>>>>>>>>>>
...<<....>>.<<........<<<<<....>>>>>.>>....>..<<<<
<<.............<<<<<<<<<<<....>>>>>>>>>>>.........
>>>>>>...>>>>>>...<<<<<<.<<<.<<<....>>>...>>>.>>>.
>>>.............>>>>>>><<<<<....>>>>>..]]...)))))}
}...>>>>>>>>>>>>>..
Receptor-Ligand Complex Structure
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PDB6agb Structural insight into precursor tRNA processing by yeast ribonuclease P.
Resolution3.48 Å
Binding residue
(original residue number in PDB)		K68 P83 K86 R122 F123 N124 Y131 R137
Binding residue
(residue number reindexed from 1)		K52 P67 K70 R106 F107 N108 Y115 R121
Enzymatic activity
Enzyme Commision number 3.1.26.5: ribonuclease P.
Gene Ontology
Molecular Function
GO:0004526 ribonuclease P activity
GO:0005515 protein binding
GO:0008270 zinc ion binding
GO:0016787 hydrolase activity
GO:0046872 metal ion binding
Biological Process
GO:0001682 tRNA 5'-leader removal
GO:0006396 RNA processing
GO:0008033 tRNA processing
GO:0034965 intronic box C/D snoRNA processing
Cellular Component
GO:0005634 nucleus
GO:0005655 nucleolar ribonuclease P complex
GO:1902555 endoribonuclease complex
GO:1990904 ribonucleoprotein complex

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Biological Process
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Cellular Component
External links
PDB RCSB:6agb, PDBe:6agb, PDBj:6agb
PDBsum6agb
PubMed30262633
UniProtP40571|RPR2_YEAST Ribonuclease P protein subunit RPR2 (Gene Name=RPR2)

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