Structure of PDB 5zwo Chain K Binding Site BS01

Receptor Information
>5zwo Chain K (length=429) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
NESTADILKQLPHERLQAVLEKIPEEDLEVRRLLSILKKPEVVENEDVQQ
RRIRLAEILMVDEIDLENINNDFFTPATSELIFARRFLINYSLERSRKRL
QKEMERHQKFNTRQELLSRRTELQRMANLELAGSQLVSTKPISAVSLSTD
DMVVATGSWAGDLQVLNSQTLQPLTQKLDSHVGKIGAIDWHPDSNNQMIS
CAEDGLIKNFQYSNEEGGLRLLGDLVGHERRISDVKYHPSGKFIGSASHD
MTWRLWDASTHQELLLQEGHDKGVFSLSFQCDGSLVCSGGMDSLSMLWDI
RSGSKVMTLAGHSKPIYTVAWSPNGYQVATGGGDGIINVWDIRKRDEGQL
NQILAHRNIVTQVRFSKEDGGKKLVSCGYDNLINVYSSDTWLKMGSLAGH
TDKIISLDISNNSHFLVSGGWDRSIKLWN
Ligand information
>5zwo Chain F (length=99) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
guucgcgaaauuuuacuucguggacauuuggucaauuugaaacaauacag
aaucagcaguuccccugcauaaggaugaaccgucaaagagauuuguuuu
<<<<<<<<<.......>>>>>>>>>.........<<<......>>>....
.................................................
Receptor-Ligand Complex Structure
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PDB5zwo Structures of the fully assembledSaccharomyces cerevisiaespliceosome before activation
Resolution3.9 Å
Binding residue
(original residue number in PDB)		N66 D68
Binding residue
(residue number reindexed from 1)		N45 D47
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003674 molecular_function
GO:0005515 protein binding
GO:0017070 U6 snRNA binding
GO:0030621 U4 snRNA binding
Biological Process
GO:0000245 spliceosomal complex assembly
GO:0000393 spliceosomal conformational changes to generate catalytic conformation
GO:0000398 mRNA splicing, via spliceosome
GO:0006397 mRNA processing
GO:0008380 RNA splicing
GO:0034247 snoRNA splicing
Cellular Component
GO:0005634 nucleus
GO:0005681 spliceosomal complex
GO:0005687 U4 snRNP
GO:0046540 U4/U6 x U5 tri-snRNP complex
GO:0071001 U4/U6 snRNP

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:5zwo, PDBe:5zwo, PDBj:5zwo
PDBsum5zwo
PubMed29794219
UniProtP20053|PRP4_YEAST U4/U6 small nuclear ribonucleoprotein PRP4 (Gene Name=PRP4)

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