Structure of PDB 5zlu Chain K Binding Site BS01

Receptor Information
>5zlu Chain K (length=150) Species: 300852 (Thermus thermophilus HB8) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
DFEEKMILIRRTARMQAGGRRFRFGALVVVGDRQGRVGLGFGKAPEVPLA
VQKAGYYARRNMVEVPLQNGTIPHEIEVEFGASKIVLKPAAPGTGVIAGA
VPRAILELAGVTDILTKELGSRNPINIAYATMEALRQLRTKADVERLRKG
Ligand information
>5zlu Chain G (length=1514) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
uggagaguuugauccuggcucagggugaacgcuggcggcgugccuaagac
augcaagucgugcgggccgcgggguuuuacuccguggucagcggcggacg
ggugaguaacgcgugggugaccuacccggaagagggggacaacccgggga
aacucgggcuaaucccccauguggacccgccccuugggguguguccaaag
ggcuuugcccgcuuccggaugggcccgcgucccaucagcuaguugguggg
guaauggcccaccaaggcgacgacggguagccggucugagaggauggccg
gccacaggggcacugagacacgggccccacuccuacgggaggcagcaguu
aggaaucuuccgcaaugggcgcaagccugacggagcgacgccgcuuggag
gaagaagcccuucgggguguaaacuccugaacccgggacgaaacccccga
cgaggggacugacgguaccgggguaauagcgccggccaacuccgugccag
cagccgcgguaauacggagggcgcgagcguuacccggauucacugggcgu
aaagggcguguaggcggccuggggcgucccaugugaaagaccacggcuca
accgugggggagcgugggauacgcucaggcuagacggugggagagggugg
uggaauucccggaguagcggugaaaugcgcagauaccgggaggaacgccg
auggcgaaggcagccaccugguccacccgugacgcugaggcgcgaaagcg
uggggagcaaaccggauuagauacccggguaguccacgcccuaaacgaug
cgcgcuaggucucugggucuccugggggccgaagcuaacgcguuaagcgc
gccgccuggggaguacggccgcaaggcugaaacucaaaggaauugacggg
ggcccgcacaagcgguggagcaugugguuuaauucgaagcaacgcgaaga
accuuaccaggccuugacaugcuagggaacccgggugaaagccuggggug
cccgcgaggggagcccuagcacaggugcugcauggccgucgucagcucgu
gccgugagguguuggguuaagucccgcaacgagcgcaacccccgccguua
guugccagcgguucggccgggcacucuaacgggacugcccgcgaaagcgg
gaggaaggaggggacgacgucuggucagcauggcccuuacggccugggcg
acacacgugcuacaaugcccacuacaaagcgaugccacccggcaacgggg
agcuaaucgcaaaaaggugggcccaguucggauuggggucugcaacccga
ccccaugaagccggaaucgcuaguaaucgcggaucagccaugccgcggug
aauacguucccgggccuuguacacaccgcccgucacgccaugggagcggg
cucuacccgaagucgccgggagccuacgggcaggcgccgaggguagggcc
cgugacuggggcgaagucguaacaagguagcuguaccggaaggugcggcu
ggaucaccuccuuu
....(((.....<<<<..))).<<<<.<<<<<...<<<<<<.........
.<<<...<<..<<..<<<<<<<<.......>>>>>>>>..>>>>......
.<<.......<<<<<<<...<<...<<<<<<<.<<<<<....<<<<<...
...>>>>>.....>>>>>....<<<<.<<<<<....>>>>>.>>>>...<
<<<...>>>>.>>>>>>>..>>.>>>>>>><<<....<<....<<<<<<<
.......>>>>>>>..>>......>>>..<<<<<<<<....>>>>...>>
>>.>>.<<<<<.<.........>>>>>>.<<<<....>>>>...>>>...
......<<.<<<....<<<<....>>>>..>>>>>.>.>>>>>...<<<<
......<<<<<..>>>>>.....>>>>....<<<<<........<<<<..
...>>>>..........>>>>>......<<<<<((....<<<<<......
...)).........>>>>>>>>>>..>>>>>>>>>..........<<.(.
.....<<<<...<<<..<<<<<.<<<<<<<<<<<......<<<<<<....
.>>>>>>....>>>>>>>>..>>>>>>>>....<<<<<<.<...<<<<<<
<....<...<<<....<<<......>>>.......>>>....>.......
...<<....>>.>>>>>>>..>.>>>.>>>...>>>...>>>>....<<<
<<<...<<...<<<<.<.....>.>>>>...>>>>>>>>..........<
<<<<<..<<<<<<<<.......>>>>>>>>...<<...)>>.....>>>>
>>..>>..<<......<<<<....>>>>....>>...>>>>...<<<..<
<<<<<<.<<..<<<<<..<<<<<<<<<<......<<........>>....
......<<<<<<<......<.<...<<..<<<<<........>>>>>...
<<......>>...>>...>.>.<<<.<<<..<<<<<<.......<<<<<.
<<<....>>>..<<<<......>>>>...>>>>>.....<<<<.<<<..<
...<<...<<<.....>>>.>>....>..>>>.....<<<<<....>>>>
>........>>>>.........>>>...>>>>>>>>>...>>>>>>>...
>>.>>>>>>>>.....<<<<<<<.....<<<..<<..<<<<....>>>>.
.>>....>>>.....>>>>>>>.............<<<<<........>>
>>>............>>>>>.....<<<<<<<..........>>>>>>>.
.....>>...>>>>>>>.>>.>.....<..<<.<.<<<..<<<..<<<<<
<<<<<<<<.....<<<<....<<<....>>>.>>>>....>>>>>>>>>>
>>>..>>>..>>>..>.>>...>.....<<<<.<<<<....>>>>.>>>>
..............
Receptor-Ligand Complex Structure
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PDB5zlu Ribosome protection by antibiotic resistance ATP-binding cassette protein.
Resolution3.6 Å
Binding residue
(original residue number in PDB)		R14 T16 R18 M19 R27 A94 P96 I101 A102 G103 T120 K121 E122 L123 R126
Binding residue
(residue number reindexed from 1)		R10 T12 R14 M15 R23 A90 P92 I97 A98 G99 T116 K117 E118 L119 R122
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003735 structural constituent of ribosome
GO:0019843 rRNA binding
Biological Process
GO:0006412 translation
Cellular Component
GO:0005737 cytoplasm
GO:0005840 ribosome
GO:0015935 small ribosomal subunit
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:5zlu, PDBe:5zlu, PDBj:5zlu
PDBsum5zlu
PubMed29712846
UniProtQ5SHQ5|RS5_THET8 Small ribosomal subunit protein uS5 (Gene Name=rpsE)

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