Structure of PDB 4p6x Chain K Binding Site BS01
Receptor Information
>4p6x Chain K (length=255) Species:
9606
(Homo sapiens) [
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ATLPQLTPTLVSLLEVIEPEVLYAGYDSSVPDSTWRIMTTLNMLGGRQVI
AAVKWAKAIPGFRNLHLDDQMTLLQYSWMALMAFALGWRSYRQSSANLLY
FAPDLIINEQRMTLPCMYDQCKHMLYVSSELHRLQVSYEEYLCMKVLLLL
STIPKDGLKSQALFDAIRMTYIKELGKAIVKREGNSSQNWQRFYQLTKLL
DSMHEVVENLLNYCFQTFLDKTMSIEFPEMLAEIITNQIPKYSNGNIKKL
LFHQK
Ligand information
>4p6x Chain H (length=13) Species:
9606
(Homo sapiens) [
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ENALLRYLLDKDD
Receptor-Ligand Complex Structure
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PDB
4p6x
Structures and mechanism for the design of highly potent glucocorticoids.
Resolution
2.5 Å
Binding residue
(original residue number in PDB)
A618 N619 E631 M634 Y640
Binding residue
(residue number reindexed from 1)
A96 N97 E109 M112 Y118
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:4p6x
,
PDBe:4p6x
,
PDBj:4p6x
PDBsum
4p6x
PubMed
24763108
UniProt
P04150
|GCR_HUMAN Glucocorticoid receptor (Gene Name=NR3C1)
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