Structure of PDB 4guo Chain K Binding Site BS01

Receptor Information
>4guo Chain K (length=201) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
HHEFIPSNTDYPGPHHFEVTFQQSSTAKSATWTYSPLLKKLYCQIAKTCP
IQIKVSTPPPPGTAIRAMPVYKKAEHVTDVVKRCPNHELGRDFNEGQSAP
ASHLIRVEGNNLSQYVDDPVTGRQSVVVPYEPPQVGTEFTTILYNFMCNS
SCVGGMNRRPILIIITLEMRDGQVLGRRSFEGRICACPGRDRKADEDHYR
E
Ligand information
Receptor-Ligand Complex Structure
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PDB4guo structure of p73 DNA binding domain complex with 12 bp DNA
Resolution3.19 Å
Binding residue
(original residue number in PDB)		S261 R293 A296 R300
Binding residue
(residue number reindexed from 1)		S151 R183 A186 R190
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0000976 transcription cis-regulatory region binding
GO:0003677 DNA binding
GO:0003700 DNA-binding transcription factor activity
Biological Process
GO:0006355 regulation of DNA-templated transcription
GO:0006915 apoptotic process
Cellular Component
GO:0005634 nucleus

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4guo, PDBe:4guo, PDBj:4guo
PDBsum4guo
PubMed
UniProtO15350|P73_HUMAN Tumor protein p73 (Gene Name=TP73)

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