Structure of PDB 4csf Chain K Binding Site BS01

Receptor Information
>4csf Chain K (length=251) Species: 11590 (Toscana virus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SDENYRDIALAFLDESADSGTINAWVNEFAYQGFDPKRIVQLVKERGTAK
GRDWKKDVKMMIVLNLVRGNKPEAMMKKMSEKGASIVANLISVYQLKEGN
PGRDTITLSRVSAAFVPWTVQALRVLSESLPVSGTTMDAIAGVTYPRAMM
HPSFAGIIDLDLPNGAGATIADAHGLFMIEFSKTINPSLRTKQANEVAAT
FEKPNMAAMSGRFFTREDKKKLLIAVGIIDEDLVLASAVVRSAEKYRAKV
G
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB4csf Structural Insights Into RNA Encapsidation and Helical Assembly of the Toscana Virus Nucleoprotein.
Resolution2.598 Å
Binding residue
(original residue number in PDB)		Y32 F35 N71 K72 G100 N101 P102 S110 R111 T185 I186 P188 R191 T201 K204 P205 M207 A208 A209 S211
Binding residue
(residue number reindexed from 1)		Y31 F34 N70 K71 G99 N100 P101 S109 R110 T184 I185 P187 R190 T200 K203 P204 M206 A207 A208 S210
Binding affinityPDBbind-CN: Kd=260nM
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Cellular Component
GO:0019013 viral nucleocapsid
GO:0019029 helical viral capsid
GO:0030430 host cell cytoplasm
GO:0042025 host cell nucleus
GO:0044172 host cell endoplasmic reticulum-Golgi intermediate compartment
GO:0044177 host cell Golgi apparatus
GO:1990904 ribonucleoprotein complex

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Molecular Function
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Cellular Component
External links
PDB RCSB:4csf, PDBe:4csf, PDBj:4csf
PDBsum4csf
PubMed24688060
UniProtP21701|NCAP_TOSV Nucleoprotein (Gene Name=N)

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