Structure of PDB 2f54 Chain K Binding Site BS01
Receptor Information
>2f54 Chain K (length=206) Species:
9606
(Homo sapiens) [
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KQQVTQIPAALSVPEGENLVLNCSFTDSAIYNLQWFRQDPGGKLTSLLLI
QSSQREQTSGRLNASLDKSAGSSTLYIAASQPGDSATYLCAVRPTSGGSY
IPTFGRGTSLIVHPYIQNPDPAVYQLRDSKSSDKSVCLFTDFDSQTNVSQ
SKDSDVYITDKCVLDMRSMDFKSNSAVAWSNKSDFACANAFNNSIIPEDT
FFPSPE
Ligand information
>2f54 Chain H (length=9) Species:
9606
(Homo sapiens) [
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SLLMWITQC
Receptor-Ligand Complex Structure
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PDB
2f54
Directed evolution of human T cell receptor CDR2 residues by phage display dramatically enhances affinity for cognate peptide-MHC without increasing apparent cross-reactivity.
Resolution
2.7 Å
Binding residue
(original residue number in PDB)
Y30 P93 T94 S95 G97 Y99
Binding residue
(residue number reindexed from 1)
Y31 P94 T95 S96 G98 Y100
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:2f54
,
PDBe:2f54
,
PDBj:2f54
PDBsum
2f54
PubMed
16600963
UniProt
P01848
|TRAC_HUMAN T cell receptor alpha chain constant (Gene Name=TRAC)
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