Structure of PDB 1yve Chain K Binding Site BS01

Receptor Information
>1yve Chain K (length=510) Species: 3562 (Spinacia oleracea) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
FDFDSSVFKKEKVTLSGHDEYIVRGGRNLFPLLPDAFKGIKQIGVIGWGS
QAPAQAQNLKDSLTEAKSDVVVKIGLRKGSNSFAEARAAGFSEENGTLGD
MWETISGSDLVLLLISDSAQADNYEKVFSHMKPNSILGLSHGFLLGHLQS
LGQDFPKNISVIAVCPKGMGPSVRRLYVQGKEVNGAGINSSFAVHQDVDG
RATDVALGWSIALGSPFTFATTLEQEYKSDIFGERGILLGAVHGIVECLF
RRYTESGMSEDLAYKNTVECITGVISKTISTKGMLALYNSLSEEGKKDFQ
AAYSASYYPSMDILYECYEDVASGSEIRSVVLAGRRFYEKEGLPAFPMGK
IDQTRMWKVGEKVRSVRPAGDLGPLYPFTAGVYVALMMAQIEILRKKGHS
YSEIINESVIEAVDSLNPFMHARGVSFMVDNCSTTARLGSRKWAPRFDYI
LSQQALVAVDNGAPINQDLISNFLSDPVHEAIGVCAQLRPSVDISVTADA
DFVRPELRQA
Ligand information
Ligand IDMG
InChIInChI=1S/Mg/q+2
InChIKeyJLVVSXFLKOJNIY-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mg+2]
CACTVS 3.341[Mg++]
FormulaMg
NameMAGNESIUM ION
ChEMBL
DrugBankDB01378
ZINC
PDB chain1yve Chain K Residue 601 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB1yve The crystal structure of plant acetohydroxy acid isomeroreductase complexed with NADPH, two magnesium ions and a herbicidal transition state analog determined at 1.65 A resolution.
Resolution1.65 Å
Binding residue
(original residue number in PDB)		H226 D315
Binding residue
(residue number reindexed from 1)		H141 D230
Annotation score1
Enzymatic activity
Catalytic site (original residue number in PDB) K252 D315 E319
Catalytic site (residue number reindexed from 1) K167 D230 E234
Enzyme Commision number 1.1.1.86: ketol-acid reductoisomerase (NADP(+)).
Gene Ontology
Molecular Function
GO:0004455 ketol-acid reductoisomerase activity
GO:0016491 oxidoreductase activity
Biological Process
GO:0009082 branched-chain amino acid biosynthetic process

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Molecular Function
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Biological Process
External links
PDB RCSB:1yve, PDBe:1yve, PDBj:1yve
PDBsum1yve
PubMed9218783
UniProtQ01292|ILV5_SPIOL Ketol-acid reductoisomerase, chloroplastic (Gene Name=AHRI)

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