Structure of PDB 1i94 Chain K Binding Site BS01

Receptor Information
>1i94 Chain K (length=123) Species: 274 (Thermus thermophilus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KKKVKRQVASGRAYIHASYNNTIVTITDPDGNPITWSSGGVIGYKGSRKG
TPYAAQLAALDAAKKAMAYGMQSVDVIVRGTGAGREQAIRALQASGLQVK
SIVDDTPVPHNGCRPKKKFRKAS
Ligand information
>1i94 Chain A (length=1514) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
uguuggagaguuugauccuggcucagggugaacgcuggcggcgugccuaa
gacaugcaagucgugcgggccgcgggguuuuacuccguggucagcggcgg
acgggugaguaacgcgugggugaccuacccggaagagggggacaacccgg
ggaaacucgggcuaaucccccauguggacccgccccuuggggugugucca
aagggcuuugcccgcuuccggaugggcccgcgucccaucagcuaguuggu
gggguaauggcccaccaaggcgacgacggguagccggucugagaggaugg
ccggccacaggggcacugagacacgggccccacuccuacgggaggcagca
guuaggaaucuuccgcaaugggcgcaagccugacggagcgacgccgcuug
gaggaagaagcccuucgggguguaaacuccugaacccgggacgaaacccc
cgacgaggggacugacgguaccgggguaauagcgccggccaacuccgugc
cagcagccgcgguaauacggagggcgcgagcguuacccggauucacuggg
cguaaagggcguguaggcggccuggggcgucccaugugaaagaccacggc
ucaaccgugggggagcgugggauacgcucaggcuagacggugggagaggg
ugguggaauucccggaguagcggugaaaugcgcagauaccgggaggaacg
ccgauggcgaaggcagccaccugguccacccgugacgcugaggcgcgaaa
gcguggggagcaaaccggauuagauacccggguaguccacgcccuaaacg
augcgcgcuaggucucugggucuccugggggccgaagcuaacgcguuaag
cgcgccgccuggggaguacggccgcaaggcugaaacucaaaggaauugac
gggggcccgcacaagcgguggagcaugugguuuaauucgaagcaacgcga
agaaccuuaccaggccuugacaugcuagggaacccgggugaaagccuggg
gugccccgcgaggggagcccuagcacaggugcugcauggccgucgucagc
ucgugccgugagguguuggguuaagucccgcaacgagcgcaacccccgcc
guuaguugccagcgguucggccgggcacucuaacgggacugcccgcgaaa
gcgggaggaaggaggggacgacgucuggucagcauggcccuuacggccug
ggcgacacacgugcuacaaugcccacuacaaagcgaugccacccggcaac
ggggagcuaaucgcaaaaaggugggcccaguucggauuggggucugcaac
ccgaccccaugaagccggaaucgcuaguaaucgcggaucagccaugccgc
ggugaauacguucccgggccuuguacacaccgcccgucacgccaugggag
cgggcucuacccgaagucgccgggagccuacgggcaggcgccgaggguag
ggcccgugacuggggcgaagucguaacaagguagcuguaccggaaggugc
ggcuggaucaccuc
.......<<<<..[.((((.>>>>.<<<<.<<<<<..<<<<<<<<..<..
<<<.<<<..<<<..<<.<<<<<<<<<<.....>>>>>>>>>>.>>>>>..
....<<.......<<<<<<<<..<<...<<<<<<<.<<<<<....<<<<<
<....>>>>>>.....>>>>>...<<<<<.<<<<<....>>>>>.>>>>>
..<<<<...>>>>.>>>>>>>..>>>>>>>>>><<<....<<<..<<<<<
<<<.......>>>>>>>>>>>......>>>..<<<<<<<<....>>>>..
.>>>>.>>.<<<<<.<.........>>>>>>.<<<<....>>>>...>>>
>>>>........<<<....<<<<....>>>>..>>>..>>.>>>>>>..<
<<<......<<<<....>>>>.....>>>>....<<<<<........<<<
<.....>>>>..........>>>>>......<<<<<(((...<<<<<...
..<<.)))>>.......>>>>>>>>>>..>>>>>>>>>..........<<
<((.....<<<<...<<<.<<<<<<<.<<<<<<<<<<......<<<<<<.
....>>>>>>....>>>>>>>>..>>>>>>>>>...<<<<<<<<...<<<
<<<<....<<<<<<<.<..<<<......>>>.....>.>>>>>>>.....
......<<....>>.>>>>>>>..>>>>>.>>>...>>>...>>>>....
<<<<<<...<<...<<<<.<.....>.>>>>...>>>>>>>>........
..<<<<<<..<<<<<<<<<<...>>>>>>>>>>...<<..))>>.....>
>>>>>.>>>.<<<......<<<<....>>>>....>>>..)))).]<<<<
<.<<<<<<<.<<.<<<<<<..<<<<<<<<<<......<<........>>.
.........<<<<<<<......<<<<<<<<..<<<<<<<....>>>>>>>
...<<<......>>>..>>>>>>>>.<<<.<<<..<<<<<<.......<<
<<<<<<<....>>>..<<<<......>>>>..>>>>>>.....<<<<.<<
<<<<<..<<...<<<.....>>>.>>...>>>>>>>.....<<<<<....
>>>>>........>>>>.........>>>...>>>>>>>>>...>>>>>>
>...>>.>>>>>>>>.....<<<<<<<.....<<<..<<..<<<<....>
>>>..>>....>>>.....>>>>>>>...........<<<<<<<......
..>>>>>>>..........>>>>>>....<<<<<<<..........>>>>
>>>......>>...>>>>>>>>>>.>>....<..<<.<.<<<<.<<<..<
<<<<<<<<<<<<...<.<<<<....<<<....>>>.>>>>.>..>>>>>>
>>>>>>>..>>>.>>>>..>.>>...>.....<<<<<<<<<....>>>>>
>>>>..........
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB1i94 Crystal structures of complexes of the small ribosomal subunit with tetracycline, edeine and IF3.
Resolution3.2 Å
Binding residue
(original residue number in PDB)		N27 G37 P39 G46 G52 S53 P115 H116 N117 R120 A128 S129
Binding residue
(residue number reindexed from 1)		N21 G31 P33 G40 G46 S47 P109 H110 N111 R114 A122 S123
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
GO:0019843 rRNA binding
Biological Process
GO:0006412 translation
Cellular Component
GO:0005840 ribosome
GO:0022627 cytosolic small ribosomal subunit
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:1i94, PDBe:1i94, PDBj:1i94
PDBsum1i94
PubMed11296217
UniProtP80376|RS11_THET8 Small ribosomal subunit protein uS11 (Gene Name=rpsK)

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