Structure of PDB 1bbr Chain K Binding Site BS01

Receptor Information
>1bbr Chain K (length=259) Species: 9913 (Bos taurus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
IVEGQDAEVGLSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYPPW
DKNFTVDDLLVRIGKHSRTRYERKVEKISMLDKIYIHPRYNWKENLDRDI
ALLKLKRPIELSDYIHPVCLPDKQTAAKLLHAGFKGRVTGWGNRRETWTT
SVAEVQPSVLQVVNLPLVERPVCKASTRIRITDNMFCAGYKPGEGKRGDA
CEGDSGGPFVMKSPYNNRWYQMGIVSWGEGCDRDGKYGFYTHVFRLKKWI
QKVIDRLGS
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB1bbr The structure of residues 7-16 of the A alpha-chain of human fibrinogen bound to bovine thrombin at 2.3-A resolution.
Resolution2.3 Å
Binding residue
(original residue number in PDB)		H57 Y60A W60D K97 E97A R173 I174 D189 A190 S195 S214 W215 G216
Binding residue
(residue number reindexed from 1)		H43 Y47 W50 K93 E94 R178 I179 D199 A200 S205 S226 W227 G228
Enzymatic activity
Enzyme Commision number 3.4.21.5: thrombin.
Gene Ontology
Molecular Function
GO:0004252 serine-type endopeptidase activity
GO:0005509 calcium ion binding
Biological Process
GO:0006508 proteolysis
GO:0007596 blood coagulation

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Molecular Function
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Biological Process
External links
PDB RCSB:1bbr, PDBe:1bbr, PDBj:1bbr
PDBsum1bbr
PubMed1560020
UniProtP00735|THRB_BOVIN Prothrombin (Gene Name=F2)

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