Structure of PDB 6zqa Chain JM Binding Site BS01

Receptor Information
>6zqa Chain JM (length=135) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SKFQEIETNLKKLPKLETGFDALANKKKKKNVLPSNDWFTLPKPDDNMRR
EVQRDLLLIKHRAALDPKRHYKKQRWEVPERFAIGTIIESTILETLMGDE
ASNKYFKRKYNEIQEKSTSGRKAHYKKMKEMRKKR
Ligand information
>6zqa Chain D2 (length=523) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
augcgaaagcaguugaagacaagugcuugucguucguuaaaauggccucg
ucaaacgguggagagagucgcuaggugaucgucagaucugccuagucucu
auacagcguguuuaauugacauggguugaugcguauugagagauacaauu
ugggaagaaauucccagaguguguuucuuuugcguuuaaccugaacaguc
ucaucgugggcaucuugcgauuccauuggugagcagcgaaggauuuggug
gauuacuagcuaauagcaaucuauuucaaagaauucaaacuugggggaau
gccuuguugaauagccggucgcaagacugugauucuucaaguguaaccuc
cucucaaaucagcgauaucaaacguaccccgugaaacaccgggguaucug
uuugguggaaccugauuagaggaaacucaaagagugcuaugguaugguga
cggagugcgcuggucaagaguguaaaagcuuuuugaacagagagcauuuc
cggcagcagagauuucagcuguu
.<<<....>>>...<<<<<<<<<..>>>>>>.>>>..............<
<<<<<<<.<<...<<<<..<<<<<<<<<<<....>>>>.>>>>>>>>>>>
...>>.>>>......>>>>>..<<<<<<..<<<<...<<<<<.<<<<.<<
<<<<<<....>>>>>>>>.>>>>.>>>>>..>>>>.>>>>>>.......<
<<<<<<<<<<...........>>>>>.>>>>>>.................
........<<<...>>>.........................<<<<<..<
<<<<<<..<<<<...<<<<<....>>>>>.>.>>>..>>>>.>>.>>>>>
>.....<<<<<<...<<<<<<<<<<<<<<<<........>>>>>>>.>.>
>>>>>>>....>>>>>>.................................
<<<<<<<<.<<<.<<<<<<<<......>>>>.>>>>.>>>...>>>>.>>
>><<<<<.<<<..>>>.>>>>>.
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6zqa 90 S pre-ribosome transformation into the primordial 40 S subunit.
Resolution4.4 Å
Binding residue
(original residue number in PDB)		R202 K203
Binding residue
(residue number reindexed from 1)		R121 K122
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003674 molecular_function
Biological Process
GO:0000447 endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0000472 endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0000480 endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0006364 rRNA processing
GO:0006396 RNA processing
GO:0042254 ribosome biogenesis
Cellular Component
GO:0005634 nucleus
GO:0005730 nucleolus

View graph for
Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6zqa, PDBe:6zqa, PDBj:6zqa
PDBsum6zqa
PubMed32943521
UniProtQ12035|FCF2_YEAST rRNA-processing protein FCF2 (Gene Name=FCF2)

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