Structure of PDB 6zqb Chain JK Binding Site BS01

Receptor Information

>6zqb Chain JK (length=42) Species: 559292 (Saccharomyces cerevisiae S288C)

SKGRKLNYSVQDPIANYEAPITSGYKWSDDQIDEFFAGLLGQ

Ligand information

>6zqb Chain D3 (length=1198)

aagauaguuaucugguugauccugccagucauaugcuugucucagccaug
cagucuaaguauaagcaauuuauacagugaaacugcgaaugcucauuaaa
ucaguuaucguuuauuugauagucaugguauaacugugguaauucuagag
cuaaaaucucgacccuuuggaagagauguauuuauuagaucaaugucuuc
ggacucuuugaugaauaacuuuucgaaucgcauggccuugugcuggcgau
gguucauucaaauuucugcccuaucaacuuucgaugguaggauaguggcc
uaccaugguuucaacggguaacggggaauaaggguucgauuccggagagg
gagccugagaaacggcuaccacauccaaggaagggcaggcuuacccaauc
cuaauucagggagguagugacaauaaauaacgauacagggcccauucggg
ucuuguaauuggaaugaguacaauguaaauaccuuaacgaggaacaauug
gagggcaagucuggugccagcagccgcgguaauuccagcuccaauagcgu
auauugcucguaguugaacuuugggcccgguuggccggucggauuuccaa
cggggccuuuauuaauagggacggucgggggcaucaguauucaauuguca
gaggugaaauucuuggauuuauugaagacuaacuacugcgaaagcauuug
ccaaggacguuuucauuaaucaagaacgaaaaacuaugccgacuagggau
cgggugguguuuuuuuaaugacccacucggcaccuuacgaggaguauggu
cgcaaggcugaaacuuaaaggaauugacggaagggcaccaccaggagugg
agccugcggaaacucaccagguccagacacaauauuugugggugguggug
caugugaugcccuuguucuggcgcgcgcuacacugacggagccagcgagu
cuaaccuuggccgagaggucuugguaaaaacuccgucggggaacgaggaa
uuccuaguaagcgcaagucaucagcuugcguugauuacgucccugcccuu
uguacacaccgcccgucgcuaguaccgauugaauggcuuagugaggccuc
aggaucugcuuagagaagggggcaacuccucucagagcggagauuuggac
aaacuuggucauuuagaggaacuaaguuuccguaggugaaccugcgga

..............................<<<<<<...<....<<<.<<
<.<<....<.....<............>....>.>>.....<<<......
.<<<..<<..<<....<<<..............<<.<<<.....>>>.>>
.....<<<<<..<......>..>>>>>....<<<<...<<<<<.<<<...
.>>>...>>>>>..>>>>.........<<<<..<<<.....>>>.>>>>.
...>>>...>>>>..>>>.<<<....<<.....<<<<<<<<.......>>
>>>>>>.>>......>>>.....<<...............>>..>>>.<<
.<<<..........>>>.>>.<.<<....>>.>.>>>>>>..<<<....<
<<.....>>>..>>>.........>.....<<<<<<<.<<<<<....>>>
>>.>>>.>>>>......<<..<...........>..>>.........<<<
<<<.......<<<....>>>..................>>>>>>..>>>>
>>...<.<<...<<<.<<.....<<<<<.<<<<<............>>>>
>.>>>>>....>>....<<<<<<.<<...<<<<..<<..<<<<<<.<...
<<<......>>>......>.>>>>>>..>>.......<<....>>...>>
>>...>>>>>.>>>...>>>...>>.>............<<...<<<..<
<<<<<<<.<<<........>>>>>>>>>>>..>>>..>>...........
.......<<.........>>.....<<<<<<<<<<<<..<<.<<<<<<..
<<<.<<<<........<<<<..<....<<<<<...>>>>>......<<<<
.......>>>>...>..>>>>>>>>.>>>.....<<<<<<<.........
...<<<..<<<<....>>>>..>>>.....>>>>>>>............>
>>>>>....<<<<<<<<.......>>>>>>>>......>>...>>>>>>>
............>>>>>..<<<<.<<....<<<<<<<<.<<.....<<..
....<<<<<<<.<<<<.<.<......>.>>>>>.>>>>>>>.....>>..
...>>.>>>>>>>>...>>.>>>>....<<<<<<<<....>>>>>>>>

Receptor-Ligand Complex Structure

Structure summary

• PDB: 6zqb 90 S pre-ribosome transformation into the primordial 40 S subunit.
• Resolution: 3.9 Å
• Binding residue (original residue number in PDB): S459 K460 R462
• Binding residue (residue number reindexed from 1): S1 K2 R4

Gene Ontology

Molecular Function

• GO:0003674 molecular_function
• GO:0005515 protein binding

Biological Process

• GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
• GO:0006364 rRNA processing
• GO:0015031 protein transport
• GO:0016192 vesicle-mediated transport

Cellular Component

• GO:0005634 nucleus
• GO:0005730 nucleolus
• GO:0030686 90S preribosome
• GO:0032040 small-subunit processome

External links

• PDB: RCSB:6zqb, PDBe:6zqb, PDBj:6zqb
• PDBsum: 6zqb
• PubMed: 32943521
• UniProt: Q06631|BFR2_YEAST Protein BFR2 (Gene Name=BFR2)