Structure of PDB 6zqg Chain JJ Binding Site BS01

Receptor Information
>6zqg Chain JJ (length=181) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KFESRKIMVPPHRMTPLRNSWTKIYPPLVEHLKLQVRMNLKTKSVELRTN
PKFTTDPGALQKGADFIKAFTLGFDLDDSIALLRLDDLYIETFEVKDVKT
LTGDHLSRAIGRIAGKDGKTKFAIENATRTRIVLADSKIHILGGFTHIRM
ARESVVSLILGSPPGKVYGNLRTVASRLKER
Ligand information
>6zqg Chain D3 (length=1387) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
uaucugguugauccugccaguagucauaugcuugucucaaagauuaagcc
augcaugucuaaguauaagcaauuuauacagugaaacugcgaauggcuca
uuaaaucaguuaucguuuauuugauaguuccuuuacuacaugguauaacu
gugguaauucuagagcuaauacaugcuuaaaaucucgacccuuuggaaga
gauguauuuauuagauaaaaaaucaaugucuucggacucuuugaugauuc
auaauaacuuuucgaaucgcauggccuugugcuggcgaugguucauucaa
auuucugcccuaucaacuuucgaugguaggauaguggccuaccaugguuu
caacggguaacggggaauaaggguucgauuccggagagggagccugagaa
acggcuaccacauccaaggaaggcagcaggcgcgcaaauuacccaauccu
aauucagggagguagugacaauaaauaacgauacagggcccauucggguc
uuguaauuggaaugaguacaauguaaauaccuuaacgaggaacaauugga
gggcaagucuggugccagcagccgcgguaauuccagcuccaauagcguau
auuauguugcaguuaaaaagcucguaguugaacuuugggcccgguuggcc
ggucggauuuccaacggggccuuuccuucuggcuaaccuugaguccuugu
ggcucuuggcgaaccaggacuuuuacuuugaaaaaauuagaguguucaaa
gcaggcguauugcucgaauauauuagcauggaauaauagaauaggacguu
ugguucuauuuuguugguuucuaggaccaucguaaugauuaauagggacg
gucgggggcaucaguauucaauugucagaggugaaauucuuggauuuauu
gaagacuaacuacugcgaaagcauuugccaaggacguuuucauuaaucaa
gaacgaaaguuaggggaucgaagaugaucagauaccgucguagucuuaac
cauaaacuaugccgacuagggaucgggugguguuuuuuuaaugacccacu
cggcaccuuacgagaaaucaaagucuuuggguucuggggggaguaugguc
gcaaggcuaaagacggaagggcaccaccaggaguggagccugcggcuuac
acgcgcgcuacacugacggagccagcgagucuaaccuuggccgagagguc
uugguaaucuugugaaacuccgucgugcuggggauagagcauuguaauua
uugcucuucaacgaggaauuccuaguaagcgcaagucaucagcuugcguu
gauuacgucccugcccuuuguacacaccgcccgucgcuaguaccggaacu
aauuccguaggugaaccugcggaaggaucauuaaaga
<..<<<<<.......>>>>>.><..<<<<<<...<.<..........<<<
.<<<..<<....<<....<<..........>>...>>.>>......<<..
......<<<..<<..<<....<<<..................<.....<<
.<<<.....>>>.>>......>.........<<<<<..<<....>>..>>
>>><.<.<<<<<<......((((((..<<<....>>>.............
.>>>>>>.>...>...<<<<..<<<.....>>>.>>>>....>>>...>>
>>..>>>.<<<....<<<....<<<<<<<<.......>>>>>>>>>>>..
....>>>...<<<.<<<<....>>>>....>>>.>>.<<.<<<.......
...>>>.>>.<.<<....>>.>...>>>>>>.........<<<....<<<
.....>>>..>>>.......>.>.....<<<<<.................
...>>.>>>......<<..<...........>..>>.........<<<<<
<.......<<<....>>>..................>>>>>>..>>>>>>
.>.......<<<[[.....<.<<...<<<.<<....<<<<<<.<<<<<..
..........>>>>>.>>>>>>....<<<<<<.........<<<......
.>>>.........>>>>>>...<<<<<.<<.......<<...<.......
>..<<<.....>>>....>>......>>.>>..>>>.........<<<..
..<<<<<.......))))))..>>>>>...>>>.....>>....<<<<<<
.<<...<<<<..<<..<<<<<<.<...<<<..(...>>>......>.>>>
>>>..>>.......<<....>>...>>>>...>>>>>.>>>...>>>...
>>.>....<<<<<<<...<...<<<<..)......>>>>...>>>>>>>>
..........<<<.<<.<<<..<<<<<<<<.<<<........>>>>>>>>
>>>..>>>...<<..]]>>...>>.....>>>.>>>..............
...........<<<<<<<<<<<<..<<.<<<<<...<<<.<<<<......
.>>>>.>>>.....<<<<<<<......<<.....<<..<<<<....>>>>
..>>....>>.......>>>>>>>...........<<<<<<.........
.>>>>>>...........>>>>>....<<<<<<<.........>>>>>>>
......>>...>>>>>>>............>>>>>..<<<<.<<>>.>>>
>.<<<<<<<<<....>>>>>>>>>.............
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6zqg 90 S pre-ribosome transformation into the primordial 40 S subunit.
Resolution3.5 Å
Binding residue
(original residue number in PDB)		H104 T107 K135 D196 H197 R200 G203 R204 G207 K208 D209 K213 G253 K258 N262 R269
Binding residue
(residue number reindexed from 1)		H12 T15 K43 D104 H105 R108 G111 R112 G115 K116 D117 K121 G161 K166 N170 R177
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0042134 rRNA primary transcript binding
GO:0051082 unfolded protein binding
Biological Process
GO:0000056 ribosomal small subunit export from nucleus
GO:0000447 endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0000472 endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0042254 ribosome biogenesis
GO:0042255 ribosome assembly
GO:0043248 proteasome assembly
Cellular Component
GO:0005634 nucleus
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0030686 90S preribosome

View graph for
Molecular Function
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Biological Process
View graph for
Cellular Component
External links
PDB RCSB:6zqg, PDBe:6zqg, PDBj:6zqg
PDBsum6zqg
PubMed32943521
UniProtQ99216|PNO1_YEAST Pre-rRNA-processing protein PNO1 (Gene Name=PNO1)

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