Structure of PDB 6gzz Chain J3 Binding Site BS01

Receptor Information
>6gzz Chain J3 (length=99) Species: 300852 (Thermus thermophilus HB8) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KIRIKLRGFDHKTLDASAQKIVEAARRSGAQVSGPIPLPTRVRRFTVIRG
PFKHKDSREHFELRTHNRLVDIINPNRKTIEQLMTLDLPTGVEIEIKTV
Ligand information
>6gzz Chain A3 (length=1506) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
uggagaguuugauccuggcucagggugaacgcuggcggcgugccuaagac
augcaagucgugcgggccgcgggguuuuacuccguggucagcggcggacg
ggugaguaacgcgugggugaccuacccggaagagggggacaacccgggga
aacucgggcuaaucccccauguggacccgccccuugggguguguccaaag
ggcuuugcccgcuuccggaugggcccgcgucccaucagcuaguugguggg
guaauggcccaccaaggcgacgacggguagccggucugagaggauggccg
gccacaggggcacugagacacgggccccacuccuacgggaggcagcaguu
aggaaucuuccgcaaugggcgcaagccugacggagcgacgccgcuuggag
gaagaagcccuucgggguguaaacuccugaacccgggacgaaacccccga
cgaggggacugacgguaccgggguaauagcgccggccaacuccgugccag
cagccgcgguaauacggagggcgcgagcguuacccggauucacugggcgu
aaagggcguguaggcggccuggggcgucccaugugaaagaccacggcuca
accgugggggagcgugggauacgcucaggcuagacggugggagagggugg
uggaauucccggaguagcggugaaaugcgcagauaccgggaggaacgccg
auggcgaaggcagccaccugguccacccgugacgcugaggcgcgaaagcg
uggggagcaaaccggauuagauacccggguaguccacgcccuaaacgaug
cgcgcuaggucucugggucuccugggggccgaagcuaacgcguuaagcgc
gccgccuggggaguacggccgcaaggcugaaacucaaaggaauugacggg
ggcccgcacaagcgguggagcaugugguuuaauucgaagcaacgcgaaga
accuuaccaggccuugacaugcuagggaacccgggugaaagccuggggug
ccccgcgaggggagcccuagcacaggugcugcauggccgucgucagcucg
ugccgugagguguuggguuaagucccgcaacgagcgcaacccccgccguu
aguugccagcgguucggccgggcacucuaacgggacugcccgcgaaagcg
ggaggaaggaggggacgacgucuggucagcauggcccuuacggccugggc
gacacacgugcuacaaugcccacuacaaagcgaugccacccggcaacggg
gagcuaaucgcaaaaaggugggcccaguucggauuggggucugcaacccg
accccaugaagccggaaucgcuaguaaucgcggaucagccaugccgcggu
gaauacguucccgggccuuguacacaccgcccgucacgccaugggagcgg
gcucuacccgaagucgccgggagccuacgggcaggcgccgaggguagggc
ccgugacuggggcgaagucguaacaagguagcuguaccggaaggugcggc
uggauc
....<<<<....(((..>>>>.<<...<<<<...<<<<<<<......<<<
.<<<..<<<..<<...........................>>>>>.....
.<<.......<<<<<<<<..<<...<<<<<....<<<.....<<<<<...
...>>>>>......>>>.....<<<<.<<<<<....>>>>>.>>>>....
<......>.....>>>>>..>>>>>>>>>><<<.....<....<<<<<<<
.......>>>>>>>..>.......>>>..<<<<<<<<....>>>>...>>
>>.>>.<<<<<.<.........>>>>>>.<<........>>...>>>>>>
......<...<<....<<<<....>>>>..>>..>.>.>>>>>>..<<<<
......<<<......>>>.....>>>>...<<<<<<......<.<<<<..
...>>>>..>.......>>>>>.>....<<<<<(((...<<<<<.....<
..))).>.......>>>>>>>>>>...>>>>..>>..........<<<((
.....<<<<...<<<.<<<<....<<<<<<<<<<......<<<<<<....
.>>>>>>....>>>>>>>..>>>...>>>>....<...<<.....<<<<<
<....<<<<<<<....<<........>>.......>>>>>>>........
...<......>.>>>>>>...>>.....>....>>>...>>>>....<<<
<<<...<<...<<<<.........>>>>...>>>>>>>>..........<
<<<<<..<<<<<<<<<<...>>>>>>>>>>...<<..))>>.....>>>>
>>.>>>.<<<......<<<<....>>>>....>>>...)))..<<<<<.<
<<<<<<....<<<<<<...<<<<<<<........<<........>>....
......<<<<.......................<........>.......
........................<.......<<<<<<<.......<<<<
<<<<....>>>..<<<<......>>>>..>>>>>......<<<<.<<<<<
<<...<..............>.....>>>>>>>.....<<<<<....>>>
>>........>>>>.......>.>>>...>>>.....>......>>.>>.
....>>>>>>>......<<<<.........<...<...<<<<....>>>>
...>.....>.........>>>>......<....<<<<<<<........>
>>>>>>....>.....>>>>>>.....<<<<<............>>>>>.
...........>>>>>>>>>>.>>....<..<<...<<<<.<<<..<<<<
<<<<<<<<<...<..<<.....<........>..>>..>..>>>>>>>>>
>>>>..>>>.>>>>....>>...>.....<<<<<<<<<....>>>>>>>>
>.....
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6gzz Cryo-EM structure of the hibernating Thermus thermophilus 100S ribosome reveals a protein-mediated dimerization mechanism.
Resolution4.13 Å
Binding residue
(original residue number in PDB)		R5 K7 H13 G36 P37 I38 P39 L40 P41 R43 V44 R45 R46 T48 P53 F54 H56 K57 S59 R60 H62 K99
Binding residue
(residue number reindexed from 1)		R3 K5 H11 G34 P35 I36 P37 L38 P39 R41 V42 R43 R44 T46 P51 F52 H54 K55 S57 R58 H60 K97
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0000049 tRNA binding
GO:0003723 RNA binding
GO:0003735 structural constituent of ribosome
GO:0019843 rRNA binding
Biological Process
GO:0006412 translation
Cellular Component
GO:0005840 ribosome
GO:0015935 small ribosomal subunit
GO:1990904 ribonucleoprotein complex

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Molecular Function
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Biological Process
View graph for
Cellular Component
External links
PDB RCSB:6gzz, PDBe:6gzz, PDBj:6gzz
PDBsum6gzz
PubMed30301898
UniProtQ5SHN7|RS10_THET8 Small ribosomal subunit protein uS10 (Gene Name=rpsJ)

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