Structure of PDB 8d3q Chain J Binding Site BS01

Receptor Information
>8d3q Chain J (length=190) Species: 272558 (Halalkalibacterium halodurans C-125) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SNEEDRYLMLSGLQHFQFCKRQWALIHIEQQWKLTVRAMPIQSKNLQISG
ICDVVEFVQDSEGIELSGVSGSYKAFPVEYKRGKPKKGDEDIVQLVAQAM
CLEEMLVCRIDKGYLFYNEIKHRVEVPITDALRDKVVQMAKEMHHYYENR
HTPKVKTGPFCNNCSLQSICLPKLMNKRSVKRYIEGRLSE
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB8d3q PAM binding ensures orientational integration during Cas4-Cas1-Cas2-mediated CRISPR adaptation.
Resolution3.9 Å
Binding residue
(original residue number in PDB)
M11 G79 I80
Binding residue
(residue number reindexed from 1)
M9 G50 I51
Enzymatic activity
Enzyme Commision number 3.1.12.1: 5' to 3' exodeoxyribonuclease (nucleoside 3'-phosphate-forming).
Gene Ontology
Molecular Function
GO:0004527 exonuclease activity
GO:0046872 metal ion binding
GO:0051536 iron-sulfur cluster binding
Biological Process
GO:0051607 defense response to virus

View graph for
Molecular Function

View graph for
Biological Process
External links
PDB RCSB:8d3q, PDBe:8d3q, PDBj:8d3q
PDBsum8d3q
PubMed36272411
UniProtA0A4Y7WTW2

[Back to BioLiP]