Structure of PDB 8a3w Chain J Binding Site BS01

Receptor Information
>8a3w Chain J (length=129) Species: 347515 (Leishmania major strain Friedlin) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
CRFRVSVALPVGAVVNCADNTGAKNLYVISVKGYHGRLNRLPSAALGDMV
MCSVKKGKPELRKKVLNAVIIRQRKSWRRKDGTVIYFEDNAGVIVNPKGE
MKGSGIAGPVAKESADLWPKISTHAPAIV
Ligand information
>8a3w Chain 2 (length=947) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
ccaacugcagaccguacucaucaccgcaucagguccccaagcauagaaug
cucugguacauagagaaagguacacucagggaagucggcaaaauagaugc
guaaguucgcaagaagcauuggcucugagggcaaaauugccaacucagaa
cugcuuacggcggggaauccaacuguauaauuaaaacauagguuugugau
gcauccaagugguguauaucgcaaacugauuucugcccagugcucuguca
acgugacgagauucaccgacgcgcggguaaacggcgggcucucuuaaggu
agccaaaugccucgucuuccaauuagagacgcgcaugaauggauuaauga
gauucccucugucccgaguuacuaucuagcgaaacgacagucaagggaac
ggacuugaagggcuaagcggggaaagaagacccuguugaguuugacucca
gucuggcucugugcgguucacuuaucgaaugaagagaccaauggguuuag
cguagucuggcuaugcaccgucuagguuccgugcuguaaacugaaccaac
gggaguuccggagucuuguuucgagacaucugccagauggggaguuuggc
uggggcggcauaucuguuacacgacaacgcagguguccuaaggcgagcuc
agugggaucucacguagaacacaagcguaaaagcuugcuugauuaacgau
uuccaguacgaaucgagacugcgaaagcaaggccagcgauccuuugcgau
gaacaaaucauaccagaggugucagaauaauuaccacagggauaaggcuu
gauccuucgaugucggcucuuccuaaccuagcggcuaaggguuggauugu
ucacccacugacagggaacgugagcuggguuuagaccgucgugagacagg
uugguuuuacccuacuuagcuggaaauugcgagaaaaauccguaagc
.......................<<......>>......<<<<<...>>>
>>........<<<<....<<<<.<<<<.<<.........<.....<<<<<
....<<..>>.....>>>>><<.<<<<<<<<<<<..>>>>>..>>>>>>.
>>..........<<<<<<<<<..<<<.........>>>..<<<<<<<...
.<<<<.....>>>>......>>>>>>>...<<..<<<..<<<<<<.<<..
..<<<<......>>>>....>>..>>>>..>>>>><<....>>.......
.<...........<<<<<.......>>>>>.....>.....>>....>>.
>>>>>>>..>..>>.>>>>>>>>.>>>>............<<<<<.....
...>>>>>..<<<<<<<..<<<.<<......<<<<.<<<<<<..<<<<<.
<<<<<<<...<<<.<.>.>>>...<<<<<.....<<<<...........<
.<<<.........>>>.>...............................<
<<<...>>>>..>>>>...>>>>>.......>>>>>>>..>>>>>...<<
<.....>>>..<<<<<<...........>>>>>>..<<...<<<<<<<..
.<<<<<..>>>>>.....<<......>>....>>>>>>>...<<...<<<
<<.......>>>>>..>>.<<<....>>>.>>.........<<<<<..<<
<.......>>>..>>>>>..........>>>>..>>>>>>.....<<.<.
>.>.>.......<<<<<.<<<<<<..<<<<<<.>>>..>>>.<<<.....
....>>>.....>>>>>..>...>>>.>>....<<<<<<<....>>>.>>
>>....>>..>>>.>>>>>>>..........................
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8a3w CRYO-EM STRUCTURE OF LEISHMANIA MAJOR 80S RIBOSOME : WILD TYPE
Resolution2.89 Å
Binding residue
(original residue number in PDB)		A18 A23 I39 S40 G43 Y44 H45 G46 R47 L48 N49 R50 L51 R84
Binding residue
(residue number reindexed from 1)		A8 A13 I29 S30 G33 Y34 H35 G36 R37 L38 N39 R40 L41 R74
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
GO:0070180 large ribosomal subunit rRNA binding
Biological Process
GO:0006412 translation
Cellular Component
GO:0005840 ribosome
GO:0022625 cytosolic large ribosomal subunit
GO:1990904 ribonucleoprotein complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8a3w, PDBe:8a3w, PDBj:8a3w
PDBsum8a3w
PubMed
UniProtE9AFK3

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