Structure of PDB 7s9u Chain J Binding Site BS01

Receptor Information
>7s9u Chain J (length=142) Species: 1423 (Bacillus subtilis) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
TPMANASTIERKWLVVDAAGKTLGRLSSEVAAILRGKHKPTYTPHVDTGD
HVIIINAEKIELTGKKLTDKIYYRHTQHPGGLKSRTALEMRTNYPEKMLE
LAIKGMLPKGSLGRQMFKKLNVYRGSEHPHEAQKPEVYELRG
Ligand information
>7s9u Chain A (length=2436) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
uuaaguuagaaagggcgcacgguggaugccuuggcacuaggagccgauga
aggacgggacgaacaccgauaugcuucggggagcuguaagcaagcuuuga
uccggagauuuccgaauggggaaacccaccacucguaauggagugguauc
cauaucugaauucauaggauaugagaaggcagacccggggaacugaaaca
ucuaaguacccggaggaagagaaagcaaaugcgauucccugaguagcggc
gagcgaaacgggaucagcccaaaccaagaggcuugccucuugggguugua
ggacacucuguacggaguuacaaaggaacgagguagaugaagaggucugg
aaaggcccgccauaggagguaacagcccuguagucaaaacuucguucucu
ccugaguggauccugaguacggcggaacacgugaaauuccgucggaaucc
gggaggaccaucucccaaggcuaaauacucccuagugaccgauagugaac
caguaccgugagggaaaggugaaaagcaccccggaaggggagugaaagag
auccugaaaccgugugccuacaaguagucagagcccguuaacgggugaug
gcgugccuuuuguagaaugaaccggcgaguuacgaucucgugcaagguua
agcagaagaugcggagccgcagcgaaagcgagucugaauagggcgcauga
guacguggucguagacccgaaaccaggugaucuacccauguccaggguga
aguucagguaacacugaauggaggcccgaacccacgcacguugaaaagug
cggggaugagguguggguaggggugaaaugccaaucgaaccuggagauag
cugguucucuccgaaauagcuuuagggcuagccucaagguaagagucuug
gagguagagcacugauuggacuaggcgaauucagucaaacuccgaaugcc
aaugacuuauccuugggagucagacugcgagugauaagauccguagucga
aagggaaacagcccagaccgccagcuaaggucccaaaguauacguuaagu
ggaaaaggauguggaguugacucugcgccgaaaauguaccggggcuaaac
guaucaccgaagcugcggacuguucuucgaacagugguaggagagcguuc
uaagggcugugaagccagaccggaaggacugguggagcgcuuagaaguga
gaaugccgguaugaguagcgaaagaggggugagaauccccuccaccgaau
gccuaagguuuccugaggaaggcucguccgcucaggguuagucgggaccu
aagccgaggccgaaaggcguaggcgauggacaacagguugauauuccugu
accaccuccucaccauuugagcaauggggggacgcaggaggauaggguaa
gcgcgguauuggauauccgcguccaagcaguuaggcugggaaauaggcaa
auccguuucccauaagccugagcugugauggcgagcgaaauauaguagcg
aaguuccugauuccacacugccaagaaaagccucuagcgaggugagaggu
gcccguaccgcaaaccgacacagguaggcgaggagagaauccuaagguga
ucgagagaacucucguuaaggaacucggcaaaaugaccccguaacuucgg
gagaaggggugcucuguuagggugcaagcccgagagagccgcagugaaua
ggcccaggcgacuguuuagcaaaaacacaggucucugcgaagccguaagg
cgaaguauaggggcugacgccuaggcgcaacgaucugggcacugucucaa
cgagagacucggugaaauuauaguaccugugaagaugcagguuacccgcg
acaggacggaaagaccccguggagcuuuacugcagccugauauugaaugu
ccuucuaacccgccgcccuuaucgggcggggagacagugucaggugggca
guuugacuggggcggucgccuccuaaaagguaacggaggcgcccaaaggu
ucccucagaaugguuggaaaucauucgcagaguguaaaggcacaagggag
cuugacugcgagaccuacaagucgagcagggacgaaagucgggcuuagug
auccggugguuccgcauggaagggccaucgcucaacggauaaaagcuacc
ccgguccgucgcgggcgcaggaaauuugagaggagcuguccuuaguacga
gaggaccgggauggacgcaccgcugguguaccaguuguucugccaagggc
aucgcuggguagcuaugugcggacgggauaagugcugaaagcaucuaagc
augaagccccccucaagaugagauuucccauuccgcaaggaaguaagauc
ccugaaagaugaucagguugauaggucugagguggaaguguggcgacaca
uggagcugacagauacuaaucgaucgaggacuuaac
<<<<<<......<<<<<<<<<<<....<<<..<<<<<<<<<<<<<.....
.<<<<<<.....((.>>>.....<<<<<<<..<<<)).....>>>.....
>>>>>>>...>>>....<<<....>>><<<<<<<......>>>>>>>.<<
<<<<<<<.........>>>>>>>.>>.>>....<<<<<<.....<.....
.>......>>>>>.>.........<<....>>...<<<<......<<...
..>>.....>>>>...<<<....<<<<<<<<....>>>>>>>>.......
<<<<<<<<.....<<<<.......<<<<<<<<<<.<<<.....<<<<...
...>>>>.((......<<<.....))>>>...>>>...>>>>>>>>>>>>
>>.>>>>>..>>>......<<<<<<<<.........>>>>>>>>......
<<<<<..((((>>>>>..>>>......>>.>>>>>>>.>>..........
.....<<....>>....>>.........<<<<....>>>>..........
...>....>>>>>>>>>>>.......<<<<..<<<<......>>>>..>>
>>...<.<........>.>.<<<<<<....<<<<<<<.<<<<<..<<<..
.<<<.....>>>...>>>...<<....>>..<<<<.....>>>>......
>>>>>.>>>>>>>..<<.<..<<<<<<<.....<<<<<<<<<..<<<...
.<<<<<<......>>>>>>.....>>>...<<<.<<<<<........>>>
>>>>>....>>>>>>>>>...<<<.....>>>......>>>>>>...>..
>.>>..<<<<<<....<<<<<....>>>>><<.<<<<<<...<<<<<<<<
<......<<...<<<.<<.............>>.>>>..>>.......>>
>>.>>>>>..>>>>>>..>>..<<<<<<<.<<......>>.>>>>>>>..
..<<<......>>>...<<<<.<<<...<<<(((.....<<<<<<.....
......<<..<<<<<<<..>>>>>>>.>>...........))).....>>
>>>>.>>>...>>>>>>><<<<<<<...>>>>>>>....>>>>>><.<<<
<<<<.<<......<<<<<.<<....>>.>>>>>...>>.>>>>>>>..>.
....>>>>>><......<<....<<<<<<.......>>>>>><<<<....
<<<<<.<<...<<<<<<...<<.....>>.>>>>>>....((<<<<.<<.
..<<<...<<<....>>>...>>>...>>...<<<<<........>>>>>
))<<<<<.<<<<<<......<<...<<<<....<<<<..<<<..<<<.<.
<<<.<.....[....>.>>>.<...<.....<<<<<.<<<<<<<.<<...
..>>>>>>>>>....>>>>>.....>....><..<<...........>>.
..>>.>>>...>>>...>>>>.........>>>>..>>..>>>>>>>>>>
>>>>>..>>.....<<......>>>>>>>.<<<<.....>>>>..>>>>.
.<<<<....<<<<<<<..<<<........<.....<<<<<....<<..>>
.....>>>>><<<<.....<<<<....>>>>....>>>>...........
.<<<<<<<<<..<<<.........>>>..<<<<<<<.....<<<....>>
>.......>>>>>>>..<<<<..>>>>...>>.>>>>>>>..>.>>>..>
>>>>>>.>>>>>>.....>.....<<<<<........>>>>>..<<<<<<
<<.<<<..............<<<<<<..<<<<<.<<<<<<<<<.<<....
...>>....<<.<<<<<.......>>>>>>>.....>>>>>>>>>..>>>
>>..<<<.......>>><<<<<<...........>>>>>>..<<.....<
<<<<....<<<<<.......>>>>>......<..[.(((.>....>>>>>
.....<<<<..<<<......>>>..>>>>.<<<....>>>.>>)))]...
...<<<<<<<.<<..))))..>>>>>>>>>.............>>>>..>
>...>>>>>>>>>>>....<<<<<<<...<<<<..<<<<<<<.....<..
..>....>>>>>>>.<<<<<...<<<<...<<<<<<<<<<<.]..>>>>>
>..>>>>>...>>>>.>>>>>...<<<.<..<<<<<...........>>>
>>...>>>>.>>>>.......>>>>>>>..<<<<....>>>>....<<<<
<<<<<.......>>>>>....<<<<<<<<.<<<....<<<<<....>>>>
>...>>>..>>>>>.>>>...>>>>....>>>>>>.
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7s9u RbgA ensures the correct timing in the maturation of the 50S subunits functional sites.
Resolution3.2 Å
Binding residue
(original residue number in PDB)		T4 P5 A9 G27 R28 S31 R38 K40 H48 T66 K69 K73 H78 L85 K86 E103 G108 M109 S114 L115 R117 H133 A135 Q136
Binding residue
(residue number reindexed from 1)		T1 P2 A6 G24 R25 S28 R35 K37 H45 T63 K66 K70 H75 L82 K83 E100 G105 M106 S111 L112 R114 H130 A132 Q133
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003729 mRNA binding
GO:0003735 structural constituent of ribosome
Biological Process
GO:0006412 translation
GO:0017148 negative regulation of translation
Cellular Component
GO:0005737 cytoplasm
GO:0005840 ribosome
GO:0022625 cytosolic large ribosomal subunit
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:7s9u, PDBe:7s9u, PDBj:7s9u
PDBsum7s9u
PubMed35141754
UniProtP70974|RL13_BACSU Large ribosomal subunit protein uL13 (Gene Name=rplM)

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