Structure of PDB 7p48 Chain J Binding Site BS01 |
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| >7p48 Chain A (length=2661)
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uuaaguuauuaagggcgcacgguggaugccuuggcacuagaagccgauga
aggacguuacuaacgacgauaugcuuuggggagcuguaaguaagcuuuga
uccagagauuuccgaauggggaaacccagcaugaguuaugucauguuauc
gauaugugaauacauagcauaucagaaggcacacccggagaacugaaaca
ucuuaguacccggaggaagagaaagaaaauucgauucccuuaguagcggc
gagcgaaaugggaagagcccaaaccaacaagcuugcuuguugggguugua
ggacaggaguuacaaaggacgacauuagacgaaucaucuggaaagaugaa
ucaaagaagguaauaauccuguagucgaaaauguugucucucuuccugag
uacgacggagcacgugaaauuccgucggaaucugggaggaccaucuccua
aggcuaaauacucucuagugaccgauagugaaccaguaccgugagggaaa
ggugaaaagcaccccggaaggggagugaaauagaaccugaaaccgugugc
uuacaaguagucagagcccguuaaugggugauggcgugccuuuuguagaa
ugaaccggcgaguuacgauuugaugcaagguuaagcaguaaauguggagc
cguagcgaaagcgagucugaauagggcguuuaguauuuggucguagaccc
gaaaccaggugaucuacccuuggucagguugaaguucagguaacacugaa
uggaggaccgaaccgacuuacguugaaaagugagcggaugaacugagggu
agcggagaaauuccaaucgaaccuggagauagcugguucucuccgaaaua
gcuuuagggcuagccucaagugaugauuauuggagguagagcacuguuug
gauucagacaaacuccgaaugccaauuaauuuaacuugggagucagaaca
ugggugauaagguccguguucgaaagggaaacagcccagaccaccagcua
aggccccaaaauauauguuaaguggaaaaggauguggcacugcgccgaaa
auguaccggggcuaaacauauuaccgaagcuguggauuguccggacaaug
guaggagagcguucuaagggcguugaagcaugaucguaaggacaugugga
gcgcuuagaagugagaaugccggugugaguagcgaaagacgggugagaau
cccguccaccgauugacuaagguuuccagaggaaggcucguccgcucugg
guuagucggguccuaagcugaggccgacaggcguaggcgauggauaacag
guugauauuccuguaccaccuauaucgauggggggacgcaguaggauagg
cgaagcgugcgauuggauugcacgucuaagcaguaaggcugaguauuagg
caaauccgguacucgggcugagcugugauggggagaucgagucguugauu
ucacacugccgagaaaagccucuagauauaggugcccguaccgcaaaccg
acacagguagucaagaugagaauucuaaggugagcgagcgaacucucguu
aaggaacucggcaaaaugaccccguaacuucgggagaaggggugcucuuu
aggguuaacgcccagaagagccgcagugaauaggcccaagcgacuguuua
ucaaaaacacaggucucugcuaaaccguaaggugauguauaggggcugac
gccugcccggugcuggaagguuaagaggagugguuagcgcgaagcuacga
aucgaagccccaguaaacggcggccguaacuauaacgguccuaagguagc
gaaauuccuugucggguaaguuccgacccgcacgaaaggcguaacgauuu
gggcacugucucaacgagagacucggugaaaucauaguaccugugaagau
gcagguuacccgcgacaggacggaaagaccccguggagcuuuacuguagc
cugauauugaaauucguggcuuucuaacccgcaccacuuaucgugguggg
agacagugucaggcgggcaguuugacuggggcggucgccuccuaaaaggu
aacggaggcgcucaaagguucccucagaaugguuggaaaucauucauaga
guguaaaggcauaagggagcuugacugcgagaccuacaagucgagcaggg
ucgaaagacggacuuagugauccggugguuccgcauggaagggccaucgc
ucaacggauaaaagcuaccccggggauaacaggcuuaucucccccaagag
uucacaucgacggggagguuuggcaccucgaugucggcucaucgcauccu
ggggcuguagucggucccaaggguugggcuguucgcccauuaaagcggua
cgcgagcuggguucagaacgucgugagacaguucggucccuauccgucgu
gggcguaggaaauuugagaggagcuguccuuaaccgggauggacauaccu
cugguguaccaguugucgugccaacggcauagcuggguagcuaugugugg
acgggauaagugcugaaagcaucuaagcaugaagccccccucaagaugag
auuucccaacuucgguuauaagaucccucaaagaugaugagguuaauagg
uucgagguggaagcauggugacauguggagcugacgaauacuaaucgauc
gaagacuuaau |
<<<<<<......<<<<<<<<<<<....{[[..[[<<<<<<<[[<<.....
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<<<<<<<.........>>>>>>>.>>.>>.....<<<<......<<....
>>.......>>>>...........<<....>>..<<<<<......<<...
..>>.....>>>>>..(((....<<<<<<<<....>>>>>>>>......<
<<<..<<<<.......<<<<<<<<<<.<<<...<<<<<......>>>>>(
(......<<<.....))>>>...>>>...>>>>>>>>>>>>>>>>>>...
..<<<<<<<<.........>>>>>>>>......<<<<<..<<<<>>>>>.
.)))......]].>>>>>>>.]]...............<<....>>....
]].........<<<<....>>>>.............}....>>>>>>>>>
>>.......<<<<..<<<<......>>>>..>>>>...<.<........>
.>.<<<<<<....<<<<<<<.<<<<<..<<<...<<<.....>>>...>>
>...<<....>>..<<<<.....>>>>.....>>>>>.>>>>>>>..<<.
<...<<<<<<.....<<<<<<<<<..<<<....<<<<<<......>>>>>
>.....>>>...<<<.<<<<<........>>>>>>>>....>>>>>>>>>
...<<<.....>>>......>>>>>>......>.>>..<<<<<<....<<
<<<....>>>>><<<<<<<<<...<<<<<<<<<.....<<<...<<<<<<
<..>>>>>>>..>>.>.....>>>>>.>>>>..>>>>>>>.>>..<<<<<
<<<<<......>>>>>>>>>>....<<<......>>>...<<<<.<<<..
.<<.(((.....<<<<<<...........<<..<<<<..>>>>.>>....
.......))).....>>>>>>..>>...>>>>>>><<<<<<..>>>>>>.
...>>>>>><.<<<<<<<.<<......<<<<<.<<....>>.>>>>>...
>>.>>>>>>>..>.....>>>>>><......<<....<<<<<<.......
>>>>>><<<<....<<<<<.<<...<<<<<<...<<.....>>.>>>>>>
....((<<<<.<<.<.<<<...<<<....>>>...>>>..>>>...<<<<
<........>>>>>))<<<<<<.<<<...<<<<....<<<<..<<<..<<
<<<.<<<<<<...(((...>>>>>><<..<<<<<..<<<.<<<<<<..<<
.....>>.>>>>>>..>>>..>>>>>...>>...<..>...>>>>>...>
>>...>>>>.........>>>>..>>>.>>>>>>>>>>..>>.....<<.
.....>>>>>>>.<<<.......>>>..>>>>..<<<<....<<<<<<<<
.<<...............<<<<<...............>>>>><<<<<<<
.<<<<....>>>>.>>>>>>>............<<<<<<<<<..<<<...
......>>>..<<<<<<<.....<<<....>>>.......>>>>>>>.<<
<<<.<<<..<<<<<<<..<<<<..<<...<<<<<<.<..>..>>>>>>..
.>>..>>>>>>>>>..>>>>><<<<<<.......>>>>>>........<.
..........<<<<<<.....>>>>>>.....>....>>>>>..>>.>>>
>>>>.....>>.>>>>>>>>.>>>>>>.....>.....<<<<<.......
.>>>>>..<<<<<<<<.(((.[[......<<<<.[[<<<<..<<<<<.<<
<<<<<<<.<<<<.<<..>>.>>>>....<<.<<<<<<.....>>>>>>>>
.....>>>>>>>>>..>>>>>..<<<<.....>>>><<<<<<........
...>>>>>>..<<...<<<<<<<...<<<<<<.......>>>>>>.....
<<.[.(((>>....>>>>>>>...<<<<..<<<......>>>..>>>>.<
<<....>>>.>>)))]......<<<<<<<.((..>>>>..))>>>>>>>.
............>>>>..]]>>>>.......<<<<...<<<<<<...<<.
......>>...>>>>>>....>>>.>.......<<<<<.<<<<<<..<<<
<<<<<<......>>>>>>>..>>.<<<<<.....>>>>>.....>>>>>.
.>...>>>.>>....<<<<<<<....>>>.>>>>....]]..)))>>>>>
>>>....<<<<<<<...<<<<..<<<<<<<.....>>>>>>>.<<<<<..
.<<<<...<<<<<<<<<<<.)))>>>>>>..>>>>>...>>>>.>>>>>.
..<<<.<..<<<<<...........>>>>>...>>>>.>>>>.......>
>>>>>>.<<<....>>>....<<<<<<<<<.......>>>>>....<<<<
<<<<.<<<....<<<<<....>>>>>...>>>..>>>>>.>>>...>>>>
....>>>>>>. |
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| PDB | 7p48 Sal-type ABC-F proteins: intrinsic and common mediators of pleuromutilin resistance by target protection in staphylococci. |
| Resolution | 2.9 Å |
Binding residue
(original residue number in PDB) | L3 H4 K7 G11 S12 R13 K14 R16 R18 G20 R21 A24 T25 G28 K29 T30 S31 G32 R33 K36 G37 Q38 K39 R41 S42 G43 R47 F50 G52 G53 Q54 L55 F58 R59 R60 P62 K63 R64 G65 F66 T67 N68 N70 R71 I76 N78 K103 N104 K110 L112 G113 N114 A130 |
Binding residue
(residue number reindexed from 1) | L3 H4 K7 G11 S12 R13 K14 R16 R18 G20 R21 A24 T25 G28 K29 T30 S31 G32 R33 K36 G37 Q38 K39 R41 S42 G43 R47 F50 G52 G53 Q54 L55 F58 R59 R60 P62 K63 R64 G65 F66 T67 N68 N70 R71 I76 N78 K103 N104 K110 L112 G113 N114 A130 |
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| Enzyme Commision number |
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