Structure of PDB 7ods Chain J Binding Site BS01

Receptor Information
>7ods Chain J (length=175) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GVIRAIVRAGLAMPGPPLGPVLGQRGVSINQFCKEFNERTKDIKEGIPLP
TKILVKPDRTFEIKIGQPTVSYFLKAAAGIEKGARQTGKEVAGLVTLKHV
YEIARIKAQDEAFALQDVPLSSVVRSIIGSARSLGIRVVKDLSSEELAAF
QKERAIFLAAQKEADLAAQEEAAKK
Ligand information
>7ods Chain A (length=1445) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
gcuaaaccuagccccaaacccacuccaccuuacuaccagacaaccuuagc
caaaccauuuacccaaauaaaguauaggcgauagaaauugaaaccuggcg
caauagauauaguaccgcaagggaaagaugaaaaauuauaaccaagcaua
auauagcaaggacuaaccccuauaccuucugcauaaugaauuaacuagaa
auaacuuugcaaggagagccaaagcuaagacccccgaaaccagacgagcu
accuaagaacagcuaaaagagcacacccgucuauguagcaaaauaguggg
aagauuuauagguagaggcgacaaaccuaccgagccuggugauagcuggu
uguccaagauagaaucuuaguucaacuuuaaauuugcccacagaacccuc
uaaauccccuuguaaauuuaacuguuaguccaaagaggaacagcucuuug
gacacuaggaaaaaaccuuguagagagaguaaaaaauuuaacacccauag
uaggccuaaaagcagccaccaauuaagaaagcguucaagcucaacacaaa
aaaucccaaacauauaacugaacuccucacacccaauuggaccaaucuau
cacccuauagaagaacuaauguuaguauaaguaacaugaaaacauucucc
uccgcauaagccugcgucagauuaaaacacugaacugacaauuaacagcc
caauaucuacaaucaaccaacaagucauuauuacccucacugucaaccca
acacaggcaugcucauaaggaaagguuaaaaaaaguaaaaggaacucggc
aaaucuuaccccgccuguuuaccaaaaacaucaccucuagcaucaccagu
auuagaggcaccgccugcuggcuccacgaggguucagcugucucuuacuu
uuaaccagugaaauugaccugcccgugaagaggcgggcauaacacagcaa
gacgagaagacccuauggagcuuuaauuuauuaaugcaaacagaaaccug
cauuaaaaauuucgguuggggcgaccucggagcagaacccaaccuccgag
caguacaugcuaagacuucaccagucaaagcgaacacucaauugauccaa
uaacuugaccaacggaacaaguuacccuagggaagcgcaauccuauucua
gaguccauaucaacaauaggguuuacgaccucguuggaucaggacauccc
gauggugcagccgcuauuaaagguucguuuguucaacgauuaaaguccua
cgugaucugaguucagaccggaguaauccaggucgguuucuaucuacuuu
caaauuccucccuguacgaaaggacaagagaaauaaggccuacuucacaa
agcgccuucccccguaaaugauaucaucucaacuuaguauacccacccca
cccaagaacaggguuuuuuuuuuuuuuuuuuuuuuuuuuuuuuuu
<<<.......<<<<....................................
.<......>...............<<.....>>.............>>.>
>.............<<....>>......................>>>...
........<<<.......>>>...<.<........>.>.<<<<<<.....
....<<<.<<..<<....>>...>>.>>>...<<.<...<<<<.<.....
<<<<<.<<<..<<<.....>>>...<<<..<<<<........>>>>.>>>
....>>>.>>>>>...<<.......>>......>.>>>>......>.>>.
.<<<<<<....<<<<....>>>><<<.<<<<<<<<<<.....<<......
....>>.....>>>>>>>>>>..>>>.<<<<<<<<<<......>>>>>>>
>>>...<<<......>>>....<<<.<<<...<..............<..
..<<<.........>>>....>.......<<<......>>>.........
..................>...>>>>>>........>>>>>>...<<<<<
......>>>>>.........>>>>>><......<<..<<<....>>><<<
<..<<<<........<<<<<..............>>>>>......<<<..
.<<<<.......................>>>>.......>>>.....<<.
.....>>.>>>>.....>>>>..<<<<...<<<<<<<<.<<.........
.......<<<<<<..<<<.........>>>...<<<<<<...........
..>>>>>>....<<<....>>>....>>.>>>>........>>.>>>>>>
>>>>>>.>>.....>.....<<<<<........>>>>>.......<<..<
<<.<<<....<<<<<.<<<<<<..<<<<<.<<<<<<<<..........>>
>>>>>>>>>>>..<<<<((((.>>>><<<<<<...........>>>>>>.
.<<.....<<<..<<<<.....>>>>..>>>.....>>.........<<<
....>>>............>>>>..>>>>>>>......<<<<<<<<<...
<<.......>>...>>>>>>>>>.....)))).<<<<<..<<<<<..<<.
<<<<<<......>>>>>>...>>.<<<<<.....>>>>>.....>>>>>.
.....>>>>>.....<<<<<<<....>>>.>>>>...>>>..>>>.>>..
.<.<<<.<<<.................>>>.>>><<<<<...<<<....>
>>.>>>>>......<<<................>>>...>.........<
<<<.......>>>>...............................
Receptor-Ligand Complex Structure
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PDB7ods Stepwise maturation of the peptidyl transferase region of human mitoribosomes.
Resolution3.1 Å
Binding residue
(original residue number in PDB)		R21 P34 K99 G100 A101 R102 Q103 T104 F130 Q133 S139 R142 S143 S147 R149 S150
Binding residue
(residue number reindexed from 1)		R4 P17 K82 G83 A84 R85 Q86 T87 F113 Q116 S122 R125 S126 S130 R132 S133
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003735 structural constituent of ribosome
GO:0005515 protein binding
GO:0070180 large ribosomal subunit rRNA binding
Biological Process
GO:0006412 translation
GO:0032543 mitochondrial translation
Cellular Component
GO:0005739 mitochondrion
GO:0005743 mitochondrial inner membrane
GO:0005761 mitochondrial ribosome
GO:0005762 mitochondrial large ribosomal subunit
GO:0005840 ribosome
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:7ods, PDBe:7ods, PDBj:7ods
PDBsum7ods
PubMed34135320
UniProtQ9Y3B7|RM11_HUMAN Large ribosomal subunit protein uL11m (Gene Name=MRPL11)

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