Structure of PDB 7c79 Chain J Binding Site BS01

Receptor Information
>7c79 Chain J (length=292) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MLVDLNVPWPQNSYADKVTSQAVNNLIKTLSTLHMLGYTHIAINFTVNHS
EKFPNDVKLLNPIDIKRRFGELMDRTGLKLYSRITLIIDDPSKGQSLSKI
SQAFDIVAALPISEKGLTLSTTNLDIDLLTFQYGSRLPTFLKHKSICSCV
NRGVKLEIVYGYALRDVQARRQFVSNVRSVIRSSRSRGIVIGSGAMSPLE
CRNILGVTSLIKNLGLPSDRCSKAMGDLASLVLLNGRLRNKSHKQTIVTG
GGSGNGDDVVNDVQGIDDVQTIKVVKRSMDAEQLGHASKRHK
Ligand information
>7c79 Chain A (length=331) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
aauccaugaccaaagaaucgucacaaaucgaagcuuacaaaauggaguaa
aauuuuguuuacucaguaauaugcuuuggguugaaagucucccaccaauu
cguaugcggaaaacguaaugagauuuaaaaauaauuguuuaaaucaacuc
auuaaggaggaugcccuuggguauucugcuucuugaccugguaccucuau
ugcaggguacugguguuuucuucgguacuggauuccguuuguauggaauc
uaaaccauaguuaugacgauugcucuuucccgugcuggaucgaguaaccc
aauggagcuuacuauucuugguccauggauu
<<<<<<<<<<<<<<.<<<<<<<......<<<<<<..........<<<<<<
<......>>>>>>>........>>>>>>[.......{.((((.<<<....
.....<<<.....>>><<<<.<..........................>>
>>><<<.<<<<<<<<....>>>>>>>>.>>>......<<<<<<<<<....
....>>>>>>>>>..........>>>...<<<<<<<<......>>>>>>>
>.............>>>>>>><<<<..<<<......>>>..>>>>...].
...)))).}...>....>>>>>>.>>>>>>>
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB7c79 Structural insight into precursor ribosomal RNA processing by ribonuclease MRP.
Resolution2.5 Å
Binding residue
(original residue number in PDB)		N151 R185 R187 K223
Binding residue
(residue number reindexed from 1)		N151 R185 R187 K223
Enzymatic activity
Enzyme Commision number 3.1.26.5: ribonuclease P.
Gene Ontology
Molecular Function
GO:0000171 ribonuclease MRP activity
GO:0003723 RNA binding
GO:0004526 ribonuclease P activity
GO:0005515 protein binding
GO:0016787 hydrolase activity
Biological Process
GO:0000294 nuclear-transcribed mRNA catabolic process, RNase MRP-dependent
GO:0000460 maturation of 5.8S rRNA
GO:0001682 tRNA 5'-leader removal
GO:0006364 rRNA processing
GO:0008033 tRNA processing
GO:0034965 intronic box C/D snoRNA processing
Cellular Component
GO:0000172 ribonuclease MRP complex
GO:0005634 nucleus
GO:0005655 nucleolar ribonuclease P complex
GO:0005829 cytosol

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:7c79, PDBe:7c79, PDBj:7c79
PDBsum7c79
PubMed32586950
UniProtP38786|RPP1_YEAST Ribonuclease P/MRP protein subunit RPP1 (Gene Name=RPP1)

[Back to BioLiP]